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Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC. Yamamoto K, et al. Nature. 2020 May;581(7806):100-105. doi: 10.1038/s41586-020-2229-5. Epub 2020 Apr 22. Nature. 2020. PMID: 32376951 Free PMC article.
Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer.
Parker SJ, Amendola CR, Hollinshead KER, Yu Q, Yamamoto K, Encarnación-Rosado J, Rose RE, LaRue MM, Sohn ASW, Biancur DE, Paulo JA, Gygi SP, Jones DR, Wang H, Philips MR, Bar-Sagi D, Mancias JD, Kimmelman AC. Parker SJ, et al. Among authors: yamamoto k. Cancer Discov. 2020 Jul;10(7):1018-1037. doi: 10.1158/2159-8290.CD-19-0959. Epub 2020 Apr 27. Cancer Discov. 2020. PMID: 32341021 Free PMC article.
Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer.
Banh RS, Biancur DE, Yamamoto K, Sohn ASW, Walters B, Kuljanin M, Gikandi A, Wang H, Mancias JD, Schneider RJ, Pacold ME, Kimmelman AC. Banh RS, et al. Among authors: yamamoto k. Cell. 2020 Nov 25;183(5):1202-1218.e25. doi: 10.1016/j.cell.2020.10.016. Epub 2020 Nov 2. Cell. 2020. PMID: 33142117 Free PMC article.
Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer.
Biancur DE, Kapner KS, Yamamoto K, Banh RS, Neggers JE, Sohn ASW, Wu W, Manguso RT, Brown A, Root DE, Aguirre AJ, Kimmelman AC. Biancur DE, et al. Among authors: yamamoto k. Cell Metab. 2021 Jan 5;33(1):199-210.e8. doi: 10.1016/j.cmet.2020.10.018. Epub 2020 Nov 4. Cell Metab. 2021. PMID: 33152323 Free PMC article.
Deletion of Histone Methyltransferase G9a Suppresses Mutant Kras-driven Pancreatic Carcinogenesis.
Kato H, Tateishi K, Fujiwara H, Ijichi H, Yamamoto K, Nakatsuka T, Kakiuchi M, Sano M, Kudo Y, Hayakawa Y, Nakagawa H, Tanaka Y, Otsuka M, Hirata Y, Tachibana M, Shinkai Y, Koike K. Kato H, et al. Among authors: yamamoto k. Cancer Genomics Proteomics. 2020 Nov-Dec;17(6):695-705. doi: 10.21873/cgp.20224. Cancer Genomics Proteomics. 2020. PMID: 33099471 Free PMC article.
Soluble VCAM-1 promotes gemcitabine resistance via macrophage infiltration and predicts therapeutic response in pancreatic cancer.
Takahashi R, Ijichi H, Sano M, Miyabayashi K, Mohri D, Kim J, Kimura G, Nakatsuka T, Fujiwara H, Yamamoto K, Kudo Y, Tanaka Y, Tateishi K, Nakai Y, Morishita Y, Soma K, Takeda N, Moses HL, Isayama H, Koike K. Takahashi R, et al. Among authors: yamamoto k. Sci Rep. 2020 Dec 3;10(1):21194. doi: 10.1038/s41598-020-78320-3. Sci Rep. 2020. PMID: 33273652 Free PMC article.
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