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Induction of human cardiomyocyte-like cells from fibroblasts by defined factors.
Wada R, Muraoka N, Inagawa K, Yamakawa H, Miyamoto K, Sadahiro T, Umei T, Kaneda R, Suzuki T, Kamiya K, Tohyama S, Yuasa S, Kokaji K, Aeba R, Yozu R, Yamagishi H, Kitamura T, Fukuda K, Ieda M. Wada R, et al. Among authors: yamakawa h. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12667-72. doi: 10.1073/pnas.1304053110. Epub 2013 Jul 16. Proc Natl Acad Sci U S A. 2013. PMID: 23861494 Free PMC article. Clinical Trial.
MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures.
Muraoka N, Yamakawa H, Miyamoto K, Sadahiro T, Umei T, Isomi M, Nakashima H, Akiyama M, Wada R, Inagawa K, Nishiyama T, Kaneda R, Fukuda T, Takeda S, Tohyama S, Hashimoto H, Kawamura Y, Goshima N, Aeba R, Yamagishi H, Fukuda K, Ieda M. Muraoka N, et al. Among authors: yamakawa h. EMBO J. 2014 Jul 17;33(14):1565-81. doi: 10.15252/embj.201387605. Epub 2014 Jun 11. EMBO J. 2014. PMID: 24920580 Free PMC article.
Single-Construct Polycistronic Doxycycline-Inducible Vectors Improve Direct Cardiac Reprogramming and Can Be Used to Identify the Critical Timing of Transgene Expression.
Umei TC, Yamakawa H, Muraoka N, Sadahiro T, Isomi M, Haginiwa S, Kojima H, Kurotsu S, Tamura F, Osakabe R, Tani H, Nara K, Miyoshi H, Fukuda K, Ieda M. Umei TC, et al. Among authors: yamakawa h. Int J Mol Sci. 2017 Aug 19;18(8):1805. doi: 10.3390/ijms18081805. Int J Mol Sci. 2017. PMID: 28825623 Free PMC article.
Direct In Vivo Reprogramming with Sendai Virus Vectors Improves Cardiac Function after Myocardial Infarction.
Miyamoto K, Akiyama M, Tamura F, Isomi M, Yamakawa H, Sadahiro T, Muraoka N, Kojima H, Haginiwa S, Kurotsu S, Tani H, Wang L, Qian L, Inoue M, Ide Y, Kurokawa J, Yamamoto T, Seki T, Aeba R, Yamagishi H, Fukuda K, Ieda M. Miyamoto K, et al. Among authors: yamakawa h. Cell Stem Cell. 2018 Jan 4;22(1):91-103.e5. doi: 10.1016/j.stem.2017.11.010. Epub 2017 Dec 21. Cell Stem Cell. 2018. PMID: 29276141 Free article.
516 results