Xue L - Search Results

1

Rational design of anti-inflammatory lipid nanoparticles for mRNA delivery.

Zhang H, Han X, Alameh MG, Shepherd SJ, Padilla MS, Xue L, Butowska K, Weissman D, Mitchell MJ. Zhang H, et al. Among authors: xue l. J Biomed Mater Res A. 2022 May;110(5):1101-1108. doi: 10.1002/jbm.a.37356. Epub 2022 Jan 25. J Biomed Mater Res A. 2022. PMID: 35076171 Free PMC article.

2

Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment.

Xue L, Gong N, Shepherd SJ, Xiong X, Liao X, Han X, Zhao G, Song C, Huang X, Zhang H, Padilla MS, Qin J, Shi Y, Alameh MG, Pochan DJ, Wang K, Long F, Weissman D, Mitchell MJ. Xue L, et al. J Am Chem Soc. 2022 Jun 8;144(22):9926-9937. doi: 10.1021/jacs.2c02706. Epub 2022 May 26. J Am Chem Soc. 2022. PMID: 35616998

3

RGD peptide-based lipids for targeted mRNA delivery and gene editing applications.

Qin J, Xue L, Gong N, Zhang H, Shepherd SJ, Haley RM, Swingle KL, Mitchell MJ. Qin J, et al. Among authors: xue l. RSC Adv. 2022 Sep 7;12(39):25397-25404. doi: 10.1039/d2ra02771b. eCollection 2022 Sep 5. RSC Adv. 2022. PMID: 36199352 Free PMC article.

4

Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis.

Han X, Gong N, Xue L, Billingsley MM, El-Mayta R, Shepherd SJ, Alameh MG, Weissman D, Mitchell MJ. Han X, et al. Among authors: xue l. Nat Commun. 2023 Jan 17;14(1):75. doi: 10.1038/s41467-022-35637-z. Nat Commun. 2023. PMID: 36650129 Free PMC article.

5

In vivo bone marrow microenvironment siRNA delivery using lipid-polymer nanoparticles for multiple myeloma therapy.

Guimarães PPG, Figueroa-Espada CG, Riley RS, Gong N, Xue L, Sewastianik T, Dennis PS, Loebel C, Chung A, Shepherd SJ, Haley RM, Hamilton AG, El-Mayta R, Wang K, Langer R, Anderson DG, Carrasco RD, Mitchell MJ. Guimarães PPG, et al. Among authors: xue l. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2215711120. doi: 10.1073/pnas.2215711120. Epub 2023 Jun 13. Proc Natl Acad Sci U S A. 2023. PMID: 37310997 Free PMC article.

6

Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines.

Han X, Alameh MG, Butowska K, Knox JJ, Lundgreen K, Ghattas M, Gong N, Xue L, Xu Y, Lavertu M, Bates P, Xu J, Nie G, Zhong Y, Weissman D, Mitchell MJ. Han X, et al. Among authors: xue l. Nat Nanotechnol. 2023 Sep;18(9):1105-1114. doi: 10.1038/s41565-023-01404-4. Epub 2023 Jun 26. Nat Nanotechnol. 2023. PMID: 37365276

7

In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity.

Gong N, Han X, Xue L, El-Mayta R, Metzloff AE, Billingsley MM, Hamilton AG, Mitchell MJ. Gong N, et al. Among authors: xue l. Nat Mater. 2023 Dec;22(12):1571-1580. doi: 10.1038/s41563-023-01646-6. Epub 2023 Sep 11. Nat Mater. 2023. PMID: 37696939

8

TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue.

Zhao G, Xue L, Weiner AI, Gong N, Adams-Tzivelekidis S, Wong J, Gentile ME, Nottingham AN, Basil MC, Lin SM, Niethamer TK, Diamond JM, Bermudez CA, Cantu E, Han X, Cao Y, Alameh MG, Weissman D, Morrisey EE, Mitchell MJ, Vaughan AE. Zhao G, et al. Among authors: xue l. Sci Transl Med. 2024 Jan 31;16(732):eadg6229. doi: 10.1126/scitranslmed.adg6229. Epub 2024 Jan 31. Sci Transl Med. 2024. PMID: 38295183

9

Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery.

Zhao G, Xue L, Geisler HC, Xu J, Li X, Mitchell MJ, Vaughan AE. Zhao G, et al. Among authors: xue l. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2314747121. doi: 10.1073/pnas.2314747121. Epub 2024 Feb 5. Proc Natl Acad Sci U S A. 2024. PMID: 38315853 Free PMC article.

10

Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager.

Gong N, Han X, Xue L, Billingsley MM, Huang X, El-Mayta R, Qin J, Sheppard NC, June CH, Mitchell MJ. Gong N, et al. Among authors: xue l. Nat Biomed Eng. 2024 Feb 20. doi: 10.1038/s41551-023-01147-6. Online ahead of print. Nat Biomed Eng. 2024. PMID: 38378820

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