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Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities.
Sun L, Dick A, Meuser ME, Huang T, Zalloum WA, Chen CH, Cherukupalli S, Xu S, Ding X, Gao P, Kang D, De Clercq E, Pannecouque C, Cocklin S, Lee KH, Liu X, Zhan P. Sun L, et al. Among authors: xu s. J Med Chem. 2020 May 14;63(9):4790-4810. doi: 10.1021/acs.jmedchem.0c00015. Epub 2020 Apr 29. J Med Chem. 2020. PMID: 32298111 Free PMC article.
Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors.
Zhang X, Sun L, Meuser ME, Zalloum WA, Xu S, Huang T, Cherukupalli S, Jiang X, Ding X, Tao Y, Kang D, De Clercq E, Pannecouque C, Dick A, Cocklin S, Liu X, Zhan P. Zhang X, et al. Among authors: xu s. Eur J Med Chem. 2021 Dec 15;226:113848. doi: 10.1016/j.ejmech.2021.113848. Epub 2021 Sep 16. Eur J Med Chem. 2021. PMID: 34592608 Free PMC article.
Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability.
Xu S, Sun L, Dick A, Zalloum WA, Huang T, Meuser ME, Zhang X, Tao Y, Cherukupalli S, Ding D, Ding X, Gao S, Jiang X, Kang D, De Clercq E, Pannecouque C, Cocklin S, Liu X, Zhan P. Xu S, et al. Eur J Med Chem. 2022 Jan 5;227:113903. doi: 10.1016/j.ejmech.2021.113903. Epub 2021 Oct 9. Eur J Med Chem. 2022. PMID: 34653770 Free PMC article.
HIV-1 capsid inhibitors: a sword to destroy the virus.
Zhang X, Xu S, Sun L, Ding D, Tao Y, Kang D, Liu X, Zhan P. Zhang X, et al. Among authors: xu s. Future Med Chem. 2022 May;14(9):605-607. doi: 10.4155/fmc-2022-0008. Epub 2022 Mar 17. Future Med Chem. 2022. PMID: 35297282 No abstract available.
Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators.
Xu S, Sun L, Barnett M, Zhang X, Ding D, Gattu A, Shi D, Taka JRH, Shen W, Jiang X, Cocklin S, De Clercq E, Pannecouque C, Goldstone DC, Liu X, Dick A, Zhan P. Xu S, et al. J Med Chem. 2023 Dec 14;66(23):16303-16329. doi: 10.1021/acs.jmedchem.3c01647. Epub 2023 Dec 6. J Med Chem. 2023. PMID: 38054267 Free PMC article.
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