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Dissecting embryonic and extraembryonic lineage crosstalk with stem cell co-culture.
Wei Y, Zhang E, Yu L, Ci B, Sakurai M, Guo L, Zhang X, Lin S, Takii S, Liu L, Liu J, Schmitz DA, Su T, Zhang J, Shen Q, Ding Y, Zhan L, Sun HX, Zheng C, Xu L, Okamura D, Ji W, Tan T, Wu J. Wei Y, et al. Among authors: xu l. Cell. 2023 Dec 21;186(26):5859-5875.e24. doi: 10.1016/j.cell.2023.11.008. Epub 2023 Dec 4. Cell. 2023. PMID: 38052213
TWIST2-mediated chromatin remodeling promotes fusion-negative rhabdomyosarcoma.
Shah AM, Guo L, Morales MG, Jaichander P, Chen K, Huang H, Cano Hernandez K, Xu L, Bassel-Duby R, Olson EN, Liu N. Shah AM, et al. Among authors: xu l. Sci Adv. 2023 Apr 28;9(17):eade8184. doi: 10.1126/sciadv.ade8184. Epub 2023 Apr 28. Sci Adv. 2023. PMID: 37115930 Free PMC article.
Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma.
Hu L, Zhang Y, Guo L, Zhong H, Xie L, Zhou J, Liao C, Yao H, Fang J, Liu H, Zhang C, Zhang H, Zhu X, Luo M, von Kriegsheim A, Li B, Luo W, Zhang X, Chen X, Mendell JT, Xu L, Kapur P, Baldwin AS, Brugarolas J, Zhang Q. Hu L, et al. Among authors: xu l. Mol Cell. 2024 Feb 15;84(4):776-790.e5. doi: 10.1016/j.molcel.2023.12.010. Epub 2024 Jan 10. Mol Cell. 2024. PMID: 38211588
Vegfc-expressing cells form heterotopic bone after musculoskeletal injury.
Vishlaghi N, Guo L, Griswold-Wheeler D, Sun Y, Booker C, Crossley JL, Bancroft AC, Juan C, Korlakunta S, Ramesh S, Pagani CA, Xu L, James AW, Tower RJ, Dellinger M, Levi B. Vishlaghi N, et al. Among authors: xu l. Cell Rep. 2024 Apr 23;43(4):114049. doi: 10.1016/j.celrep.2024.114049. Epub 2024 Apr 3. Cell Rep. 2024. PMID: 38573853 Free article.
The AHR target gene scinderin activates the WNT pathway by facilitating the nuclear translocation of β-catenin.
Perez-Castro L, Venkateswaran N, Garcia R, Hao YH, Lafita-Navarro MC, Kim J, Segal D, Saponzik E, Chang BJ, Fiolka R, Danuser G, Xu L, Brabletz T, Conacci-Sorrell M. Perez-Castro L, et al. Among authors: xu l. J Cell Sci. 2022 Oct 15;135(20):jcs260028. doi: 10.1242/jcs.260028. Epub 2022 Oct 27. J Cell Sci. 2022. PMID: 36148682 Free PMC article.
WILMS TUMOR MUTATIONAL SUBCLASSES CONVERGE TO DRIVE CCND2 OVEREXPRESSION.
Xu L, Desai K, Kim J, Zhou Q, Guo L, Xiao X, Zhang Y, Zhou L, Yuksel A, Catchpoole DR, Amatruda JF, Chen KS. Xu L, et al. medRxiv [Preprint]. 2023 Feb 2:2023.01.30.23285117. doi: 10.1101/2023.01.30.23285117. medRxiv. 2023. PMID: 36778325 Free PMC article. Preprint.
Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer.
Lin CC, Chang TC, Wang Y, Guo L, Gao Y, Bikorimana E, Lemoff A, Fang YV, Zhang H, Zhang Y, Ye D, Soria-Bretones I, Servetto A, Lee KM, Luo X, Otto JJ, Akamatsu H, Napolitano F, Mani R, Cescon DW, Xu L, Xie Y, Mendell JT, Hanker AB, Arteaga CL. Lin CC, et al. Among authors: xu l. Res Sq [Preprint]. 2023 Jul 10:rs.3.rs-2966905. doi: 10.21203/rs.3.rs-2966905/v1. Res Sq. 2023. PMID: 37502925 Free PMC article. Updated. Preprint.
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