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Integration of metabolomics and proteomics reveals the underlying hepatotoxic mechanism of perfluorooctane sulfonate (PFOS) and 6:2 chlorinated polyfluoroalkyl ether sulfonic acid (6:2 Cl-PFESA) in primary human hepatocytes.
Li C, Jiang L, Qi Y, Zhang D, Liu X, Han W, Ma W, Xu L, Jin Y, Luo J, Zhao K, Yu D. Li C, et al. Among authors: xu l. Ecotoxicol Environ Saf. 2023 Jan 1;249:114361. doi: 10.1016/j.ecoenv.2022.114361. Epub 2022 Dec 9. Ecotoxicol Environ Saf. 2023. PMID: 36508832 Free article.
Human health risk assessment of 6:2 Cl-PFESA through quantitative in vitro to in vivo extrapolation by integrating cell-based assays, an epigenetic key event, and physiologically based pharmacokinetic modeling.
Li C, Jiang L, Zhang D, Qi Y, Wang X, Jin Y, Liu X, Lin Y, Luo J, Xu L, Zhao K, Yu D. Li C, et al. Among authors: xu l. Environ Int. 2023 Mar;173:107846. doi: 10.1016/j.envint.2023.107846. Epub 2023 Feb 21. Environ Int. 2023. PMID: 36842380 Free article.
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