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2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) activates Aryl hydrocarbon receptor (AhR) mediated ROS and NLRP3 inflammasome/p38 MAPK pathway inducing necrosis in cochlear hair cells.
Tang J, Hu B, Zheng H, Qian X, Zhang Y, Zhu J, Xu G, Chen D, Jin X, Li W, Xu L. Tang J, et al. Among authors: xu l, xu g. Ecotoxicol Environ Saf. 2021 Sep 15;221:112423. doi: 10.1016/j.ecoenv.2021.112423. Epub 2021 Jun 17. Ecotoxicol Environ Saf. 2021. PMID: 34146985 Free article.
Transcriptomics-based analysis of co-exposure of cadmium (Cd) and 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) indicates mitochondrial dysfunction induces NLRP3 inflammasome and inflammatory cell death in renal tubular epithelial cells.
Zhang Y, Hu B, Qian X, Xu G, Jin X, Chen D, Tang J, Xu L. Zhang Y, et al. Among authors: xu l, xu g. Ecotoxicol Environ Saf. 2022 Aug;241:113790. doi: 10.1016/j.ecoenv.2022.113790. Epub 2022 Jun 23. Ecotoxicol Environ Saf. 2022. PMID: 35753275 Free article.
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