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BRD4 inhibitor inhibits colorectal cancer growth and metastasis.
Hu Y, Zhou J, Ye F, Xiong H, Peng L, Zheng Z, Xu F, Cui M, Wei C, Wang X, Wang Z, Zhu H, Lee P, Zhou M, Jiang B, Zhang DY. Hu Y, et al. Among authors: xu f. Int J Mol Sci. 2015 Jan 16;16(1):1928-48. doi: 10.3390/ijms16011928. Int J Mol Sci. 2015. PMID: 25603177 Free PMC article.
BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice.
Cheung K, Lu G, Sharma R, Vincek A, Zhang R, Plotnikov AN, Zhang F, Zhang Q, Ju Y, Hu Y, Zhao L, Han X, Meslamani J, Xu F, Jaganathan A, Shen T, Zhu H, Rusinova E, Zeng L, Zhou J, Yang J, Peng L, Ohlmeyer M, Walsh MJ, Zhang DY, Xiong H, Zhou MM. Cheung K, et al. Among authors: xu f. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2952-2957. doi: 10.1073/pnas.1615601114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265070 Free PMC article.
T follicular helper cells restricted by IRF8 contribute to T cell-mediated inflammation.
Zhang R, Qi CF, Hu Y, Shan Y, Hsieh YP, Xu F, Lu G, Dai J, Gupta M, Cui M, Peng L, Yang J, Xue Q, Chen-Liang R, Chen K, Zhang Y, Fung-Leung WP, Mora JR, Li L, Morse HC 3rd, Ozato K, Heeger PS, Xiong H. Zhang R, et al. Among authors: xu f. J Autoimmun. 2019 Jan;96:113-122. doi: 10.1016/j.jaut.2018.09.001. Epub 2018 Sep 19. J Autoimmun. 2019. PMID: 30241692 Free PMC article.
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