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MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program.
Wang Y, Zhang L, Wu GR, Zhou Q, Yue H, Rao LZ, Yuan T, Mo B, Wang FX, Chen LM, Sun F, Song J, Xiong F, Zhang S, Yu Q, Yang P, Xu Y, Zhao J, Zhang H, Xiong W, Wang CY. Wang Y, et al. Among authors: xiong f, xiong w. Sci Adv. 2021 Jan 1;7(1):eabb6075. doi: 10.1126/sciadv.abb6075. Print 2021 Jan. Sci Adv. 2021. PMID: 33277324 Free PMC article.
The methyl-CpG-binding domain 2 facilitates pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation.
Wang Y, Zhang L, Huang T, Wu GR, Zhou Q, Wang FX, Chen LM, Sun F, Lv Y, Xiong F, Zhang S, Yu Q, Yang P, Gu W, Xu Y, Zhao J, Zhang H, Xiong W, Wang CY. Wang Y, et al. Among authors: xiong f, xiong w. Eur Respir J. 2022 Sep 29;60(3):2003697. doi: 10.1183/13993003.03697-2020. Print 2022 Sep. Eur Respir J. 2022. PMID: 35086828 Free PMC article.
Loss of ubiquitin-conjugating enzyme E2 (Ubc9) in macrophages exacerbates multiple low-dose streptozotocin-induced diabetes by attenuating M2 macrophage polarization.
Wang F, Sun F, Luo J, Yue T, Chen L, Zhou H, Zhang J, Yang C, Luo X, Zhou Q, Zhu H, Li J, Yang P, Xiong F, Yu Q, Zhang H, Zhang W, Xu A, Zhou Z, Lu Q, Eizirik DL, Zhang S, Wang CY. Wang F, et al. Among authors: xiong f. Cell Death Dis. 2019 Nov 26;10(12):892. doi: 10.1038/s41419-019-2130-z. Cell Death Dis. 2019. PMID: 31767832 Free PMC article.
Blockade of JAK2 protects mice against hypoxia-induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation.
Zhang L, Wang Y, Wu G, Rao L, Wei Y, Yue H, Yuan T, Yang P, Xiong F, Zhang S, Zhou Q, Chen Z, Li J, Mo BW, Zhang H, Xiong W, Wang CY. Zhang L, et al. Among authors: xiong f, xiong w. Cell Prolif. 2020 Feb;53(2):e12742. doi: 10.1111/cpr.12742. Epub 2020 Jan 14. Cell Prolif. 2020. PMID: 31943454 Free PMC article.
Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD-induced obesity by enhancing H3K36me2 at the Pparg locus.
Chen L, Zhang J, Zou Y, Wang F, Li J, Sun F, Luo X, Zhang M, Guo Y, Yu Q, Yang P, Zhou Q, Chen Z, Zhang H, Gong Q, Zhao J, Eizirik DL, Zhou Z, Xiong F, Zhang S, Wang CY. Chen L, et al. Among authors: xiong f. Cell Death Differ. 2021 Jun;28(6):1880-1899. doi: 10.1038/s41418-020-00714-7. Epub 2021 Jan 18. Cell Death Differ. 2021. PMID: 33462408 Free PMC article.
1,729 results