Xiao T - Search Results

1

Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations.

Jeselsohn R, Bergholz JS, Pun M, Cornwell M, Liu W, Nardone A, Xiao T, Li W, Qiu X, Buchwalter G, Feiglin A, Abell-Hart K, Fei T, Rao P, Long H, Kwiatkowski N, Zhang T, Gray N, Melchers D, Houtman R, Liu XS, Cohen O, Wagle N, Winer EP, Zhao J, Brown M. Jeselsohn R, et al. Among authors: xiao t. Cancer Cell. 2018 Feb 12;33(2):173-186.e5. doi: 10.1016/j.ccell.2018.01.004. Cancer Cell. 2018. PMID: 29438694 Free PMC article.

2

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens.

Li W, Xu H, Xiao T, Cong L, Love MI, Zhang F, Irizarry RA, Liu JS, Brown M, Liu XS. Li W, et al. Among authors: xiao t. Genome Biol. 2014;15(12):554. doi: 10.1186/s13059-014-0554-4. Genome Biol. 2014. PMID: 25476604 Free PMC article.

3

Sequence determinants of improved CRISPR sgRNA design.

Xu H, Xiao T, Chen CH, Li W, Meyer CA, Wu Q, Wu D, Cong L, Zhang F, Liu JS, Brown M, Liu XS. Xu H, et al. Among authors: xiao t. Genome Res. 2015 Aug;25(8):1147-57. doi: 10.1101/gr.191452.115. Epub 2015 Jun 10. Genome Res. 2015. PMID: 26063738 Free PMC article.

4

Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR.

Li W, Köster J, Xu H, Chen CH, Xiao T, Liu JS, Brown M, Liu XS. Li W, et al. Among authors: xiao t. Genome Biol. 2015 Dec 16;16:281. doi: 10.1186/s13059-015-0843-6. Genome Biol. 2015. PMID: 26673418 Free PMC article.

5

High-dimensional genomic data bias correction and data integration using MANCIE.

Zang C, Wang T, Deng K, Li B, Hu S, Qin Q, Xiao T, Zhang S, Meyer CA, He HH, Brown M, Liu JS, Xie Y, Liu XS. Zang C, et al. Among authors: xiao t. Nat Commun. 2016 Apr 13;7:11305. doi: 10.1038/ncomms11305. Nat Commun. 2016. PMID: 27072482 Free PMC article.

6

Modeling cis-regulation with a compendium of genome-wide histone H3K27ac profiles.

Wang S, Zang C, Xiao T, Fan J, Mei S, Qin Q, Wu Q, Li X, Xu K, He HH, Brown M, Meyer CA, Liu XS. Wang S, et al. Among authors: xiao t. Genome Res. 2016 Oct;26(10):1417-1429. doi: 10.1101/gr.201574.115. Epub 2016 Jul 27. Genome Res. 2016. PMID: 27466232 Free PMC article.

7

Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library.

Zhu S, Li W, Liu J, Chen CH, Liao Q, Xu P, Xu H, Xiao T, Cao Z, Peng J, Yuan P, Brown M, Liu XS, Wei W. Zhu S, et al. Among authors: xiao t. Nat Biotechnol. 2016 Dec;34(12):1279-1286. doi: 10.1038/nbt.3715. Epub 2016 Oct 31. Nat Biotechnol. 2016. PMID: 27798563 Free PMC article.

8

Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL-/- clear cell renal carcinoma.

Gao W, Li W, Xiao T, Liu XS, Kaelin WG Jr. Gao W, et al. Among authors: xiao t. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1027-1032. doi: 10.1073/pnas.1619726114. Epub 2017 Jan 12. Proc Natl Acad Sci U S A. 2017. PMID: 28082722 Free PMC article.

9

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

Fei T, Chen Y, Xiao T, Li W, Cato L, Zhang P, Cotter MB, Bowden M, Lis RT, Zhao SG, Wu Q, Feng FY, Loda M, He HH, Liu XS, Brown M. Fei T, et al. Among authors: xiao t. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5207-E5215. doi: 10.1073/pnas.1617467114. Epub 2017 Jun 13. Proc Natl Acad Sci U S A. 2017. PMID: 28611215 Free PMC article.

10

Improved design and analysis of CRISPR knockout screens.

Chen CH, Xiao T, Xu H, Jiang P, Meyer CA, Li W, Brown M, Liu XS. Chen CH, et al. Among authors: xiao t. Bioinformatics. 2018 Dec 1;34(23):4095-4101. doi: 10.1093/bioinformatics/bty450. Bioinformatics. 2018. PMID: 29868757 Free PMC article.

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