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A framework for in vitro systems toxicology assessment of e-liquids.
Iskandar AR, Gonzalez-Suarez I, Majeed S, Marescotti D, Sewer A, Xiang Y, Leroy P, Guedj E, Mathis C, Schaller JP, Vanscheeuwijck P, Frentzel S, Martin F, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: xiang y. Toxicol Mech Methods. 2016 Jul;26(6):389-413. doi: 10.3109/15376516.2016.1170251. Epub 2016 Apr 26. Toxicol Mech Methods. 2016. PMID: 27117495 Free PMC article.
Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers.
Mathis C, Poussin C, Weisensee D, Gebel S, Hengstermann A, Sewer A, Belcastro V, Xiang Y, Ansari S, Wagner S, Hoeng J, Peitsch MC. Mathis C, et al. Among authors: xiang y. Am J Physiol Lung Cell Mol Physiol. 2013 Apr 1;304(7):L489-503. doi: 10.1152/ajplung.00181.2012. Epub 2013 Jan 25. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 23355383 Free PMC article.
Strengths and limitations of microarray-based phenotype prediction: lessons learned from the IMPROVER Diagnostic Signature Challenge.
Tarca AL, Lauria M, Unger M, Bilal E, Boue S, Kumar Dey K, Hoeng J, Koeppl H, Martin F, Meyer P, Nandy P, Norel R, Peitsch M, Rice JJ, Romero R, Stolovitzky G, Talikka M, Xiang Y, Zechner C; IMPROVER DSC Collaborators. Tarca AL, et al. Among authors: xiang y. Bioinformatics. 2013 Nov 15;29(22):2892-9. doi: 10.1093/bioinformatics/btt492. Epub 2013 Aug 20. Bioinformatics. 2013. PMID: 23966112 Free PMC article.
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes.
Kogel U, Schlage WK, Martin F, Xiang Y, Ansari S, Leroy P, Vanscheeuwijck P, Gebel S, Buettner A, Wyss C, Esposito M, Hoeng J, Peitsch MC. Kogel U, et al. Among authors: xiang y. Food Chem Toxicol. 2014 Jun;68:204-17. doi: 10.1016/j.fct.2014.02.034. Epub 2014 Mar 12. Food Chem Toxicol. 2014. PMID: 24632068 Free article.
In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures.
Schlage WK, Iskandar AR, Kostadinova R, Xiang Y, Sewer A, Majeed S, Kuehn D, Frentzel S, Talikka M, Geertz M, Mathis C, Ivanov N, Hoeng J, Peitsch MC. Schlage WK, et al. Among authors: xiang y. Toxicol Mech Methods. 2014 Oct;24(7):470-87. doi: 10.3109/15376516.2014.943441. Epub 2014 Sep 11. Toxicol Mech Methods. 2014. PMID: 25046638 Free PMC article.
Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts.
Iskandar AR, Xiang Y, Frentzel S, Talikka M, Leroy P, Kuehn D, Guedj E, Martin F, Mathis C, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: xiang y. Toxicol Sci. 2015 Sep;147(1):207-21. doi: 10.1093/toxsci/kfv122. Epub 2015 Jun 16. Toxicol Sci. 2015. PMID: 26085348 Free PMC article.
Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model.
Luettich K, Xiang Y, Iskandar A, Sewer A, Martin F, Talikka M, Vanscheeuwijck P, Berges A, Veljkovic E, Gonzalez-Suarez I, Schlage W, Hoeng J, Peitsch M. Luettich K, et al. Among authors: xiang y. Interdiscip Toxicol. 2014 Jun;7(2):73-84. doi: 10.2478/intox-2014-0010. Epub 2014 Nov 15. Interdiscip Toxicol. 2014. PMID: 26109882 Free PMC article.
7,352 results