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LION: a simple and rapid method to achieve CRISPR gene editing.
Xiang X, Luo L, Nodzyński M, Li C, Han P, Dou H, Petersen TS, Liang X, Pan X, Qu K, Yang L, Dang Y, Liu X, Bolund L, Zhang X, Tong G, Xing Y, Luo Y, Lin L. Xiang X, et al. Cell Mol Life Sci. 2019 Jul;76(13):2633-2645. doi: 10.1007/s00018-019-03064-x. Epub 2019 Mar 18. Cell Mol Life Sci. 2019. PMID: 30887099
Efficient correction of Duchenne muscular dystrophy mutations by SpCas9 and dual gRNAs.
Xiang X, Zhao X, Pan X, Dong Z, Yu J, Li S, Liang X, Han P, Qu K, Jensen JB, Farup J, Wang F, Petersen TS, Bolund L, Teng H, Lin L, Luo Y. Xiang X, et al. Mol Ther Nucleic Acids. 2021 Mar 13;24:403-415. doi: 10.1016/j.omtn.2021.03.005. eCollection 2021 Jun 4. Mol Ther Nucleic Acids. 2021. PMID: 33868784 Free PMC article.
Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning.
Xiang X, Corsi GI, Anthon C, Qu K, Pan X, Liang X, Han P, Dong Z, Liu L, Zhong J, Ma T, Wang J, Zhang X, Jiang H, Xu F, Liu X, Xu X, Wang J, Yang H, Bolund L, Church GM, Lin L, Gorodkin J, Luo Y. Xiang X, et al. Nat Commun. 2021 May 28;12(1):3238. doi: 10.1038/s41467-021-23576-0. Nat Commun. 2021. PMID: 34050182 Free PMC article.
Massively targeted evaluation of therapeutic CRISPR off-targets in cells.
Pan X, Qu K, Yuan H, Xiang X, Anthon C, Pashkova L, Liang X, Han P, Corsi GI, Xu F, Liu P, Zhong J, Zhou Y, Ma T, Jiang H, Liu J, Wang J, Jessen N, Bolund L, Yang H, Xu X, Church GM, Gorodkin J, Lin L, Luo Y. Pan X, et al. Among authors: xiang x. Nat Commun. 2022 Jul 13;13(1):4049. doi: 10.1038/s41467-022-31543-6. Nat Commun. 2022. PMID: 35831290 Free PMC article.
3,103 results