Xiang M - Search Results

1

Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation.

Stevens AM, Xiang M, Heppler LN, Tošić I, Jiang K, Munoz JO, Gaikwad AS, Horton TM, Long X, Narayanan P, Seashore EL, Terrell MC, Rashid R, Krueger MJ, Mangubat-Medina AE, Ball ZT, Sumazin P, Walker SR, Hamada Y, Oyadomari S, Redell MS, Frank DA. Stevens AM, et al. Among authors: xiang m. Blood Adv. 2019 Dec 23;3(24):4215-4227. doi: 10.1182/bloodadvances.2019000499. Blood Adv. 2019. PMID: 31856268 Free PMC article.

2

The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations.

Nelson EA, Walker SR, Xiang M, Weisberg E, Bar-Natan M, Barrett R, Liu S, Kharbanda S, Christie AL, Nicolais M, Griffin JD, Stone RM, Kung AL, Frank DA. Nelson EA, et al. Among authors: xiang m. Genes Cancer. 2012 Jul;3(7-8):503-11. doi: 10.1177/1947601912466555. Genes Cancer. 2012. PMID: 23264850 Free PMC article.

3

Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancer.

Walker SR, Xiang M, Frank DA. Walker SR, et al. Among authors: xiang m. Mol Cell Endocrinol. 2014 Jan 25;382(1):616-621. doi: 10.1016/j.mce.2013.03.010. Epub 2013 Mar 24. Mol Cell Endocrinol. 2014. PMID: 23531638 Free PMC article. Review.

4

STAT signaling in the pathogenesis and treatment of myeloid malignancies.

Bar-Natan M, Nelson EA, Xiang M, Frank DA. Bar-Natan M, et al. Among authors: xiang m. JAKSTAT. 2012 Apr 1;1(2):55-64. doi: 10.4161/jkst.20006. JAKSTAT. 2012. PMID: 24058751 Free PMC article. Review.

5

Targeting STAT5 in hematologic malignancies through inhibition of the bromodomain and extra-terminal (BET) bromodomain protein BRD2.

Liu S, Walker SR, Nelson EA, Cerulli R, Xiang M, Toniolo PA, Qi J, Stone RM, Wadleigh M, Bradner JE, Frank DA. Liu S, et al. Among authors: xiang m. Mol Cancer Ther. 2014 May;13(5):1194-205. doi: 10.1158/1535-7163.MCT-13-0341. Epub 2014 Jan 16. Mol Cancer Ther. 2014. PMID: 24435449 Free PMC article.

6

STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypes.

Xiang M, Birkbak NJ, Vafaizadeh V, Walker SR, Yeh JE, Liu S, Kroll Y, Boldin M, Taganov K, Groner B, Richardson AL, Frank DA. Xiang M, et al. Sci Signal. 2014 Jan 28;7(310):ra11. doi: 10.1126/scisignal.2004497. Sci Signal. 2014. PMID: 24473196 Free PMC article.

7

The transcriptional modulator BCL6 as a molecular target for breast cancer therapy.

Walker SR, Liu S, Xiang M, Nicolais M, Hatzi K, Giannopoulou E, Elemento O, Cerchietti L, Melnick A, Frank DA. Walker SR, et al. Among authors: xiang m. Oncogene. 2015 Feb 26;34(9):1073-82. doi: 10.1038/onc.2014.61. Epub 2014 Mar 24. Oncogene. 2015. PMID: 24662818 Free PMC article.

8

STAT3 Activity and Function in Cancer: Modulation by STAT5 and miR-146b.

Walker SR, Xiang M, Frank DA. Walker SR, et al. Among authors: xiang m. Cancers (Basel). 2014 Apr 23;6(2):958-68. doi: 10.3390/cancers6020958. Cancers (Basel). 2014. PMID: 24762632 Free PMC article.

9

Gene expression-based discovery of atovaquone as a STAT3 inhibitor and anticancer agent.

Xiang M, Kim H, Ho VT, Walker SR, Bar-Natan M, Anahtar M, Liu S, Toniolo PA, Kroll Y, Jones N, Giaccone ZT, Heppler LN, Ye DQ, Marineau JJ, Shaw D, Bradner JE, Blonquist T, Neuberg D, Hetz C, Stone RM, Soiffer RJ, Frank DA. Xiang M, et al. Blood. 2016 Oct 6;128(14):1845-1853. doi: 10.1182/blood-2015-07-660506. Epub 2016 Aug 16. Blood. 2016. PMID: 27531676 Free PMC article.

10

CDK5RAP3 is a co-factor for the oncogenic transcription factor STAT3.

Egusquiaguirre SP, Liu S, Tošić I, Jiang K, Walker SR, Nicolais M, Saw TY, Xiang M, Bartel K, Nelson EA, Frank DA. Egusquiaguirre SP, et al. Among authors: xiang m. Neoplasia. 2020 Jan;22(1):47-59. doi: 10.1016/j.neo.2019.10.002. Epub 2019 Nov 22. Neoplasia. 2020. PMID: 31765941 Free PMC article.

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