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Therapeutic targeting of CPSF3-dependent transcriptional termination in ovarian cancer.
Shen P, Ye K, Xiang H, Zhang Z, He Q, Zhang X, Cai MC, Chen J, Sun Y, Lin L, Qi C, Zhang M, Cheung LWT, Shi T, Yin X, Li Y, Di W, Zang R, Tan L, Zhuang G. Shen P, et al. Among authors: xiang h. Sci Adv. 2023 Nov 24;9(47):eadj0123. doi: 10.1126/sciadv.adj0123. Epub 2023 Nov 22. Sci Adv. 2023. PMID: 37992178 Free PMC article.
HOIP modulates the stability of GPx4 by linear ubiquitination.
Dong K, Wei R, Jin T, Zhang M, Shen J, Xiang H, Shan B, Yuan J, Li Y. Dong K, et al. Among authors: xiang h. Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2214227119. doi: 10.1073/pnas.2214227119. Epub 2022 Oct 24. Proc Natl Acad Sci U S A. 2022. PMID: 36279464 Free PMC article.
Selective Covalent Targeting of Pyruvate Kinase M2 Using Arsenous Warheads.
Wang J, Zhou S, Cheng Y, Cheng L, Qin Y, Zhang Z, Bi A, Xiang H, He X, Tian X, Liu W, Zhang J, Peng C, Zhu Z, Huang M, Li Y, Zhuang G, Tan L. Wang J, et al. Among authors: xiang h. J Med Chem. 2023 Feb 23;66(4):2608-2621. doi: 10.1021/acs.jmedchem.2c01563. Epub 2023 Feb 1. J Med Chem. 2023. PMID: 36723914
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1.
Qin Y, Li D, Qi C, Xiang H, Meng H, Liu J, Zhou S, Gong X, Li Y, Xu G, Zu R, Xie H, Xu Y, Xu G, Zhang Z, Chen S, Pan L, Li Y, Tan L. Qin Y, et al. Among authors: xiang h. Acta Pharm Sin B. 2024 Jan;14(1):319-334. doi: 10.1016/j.apsb.2023.10.021. Epub 2023 Nov 8. Acta Pharm Sin B. 2024. PMID: 38261830 Free PMC article.
3,239 results