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Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health.
Kusuyama J, Alves-Wagner AB, Conlin RH, Makarewicz NS, Albertson BG, Prince NB, Kobayashi S, Kozuka C, Møller M, Bjerre M, Fuglsang J, Miele E, Middelbeek RJW, Xiudong Y, Xia Y, Garneau L, Bhattacharjee J, Aguer C, Patti ME, Hirshman MF, Jessen N, Hatta T, Ovesen PG, Adamo KB, Nozik-Grayck E, Goodyear LJ. Kusuyama J, et al. Among authors: xia y. Cell Metab. 2021 May 4;33(5):939-956.e8. doi: 10.1016/j.cmet.2021.03.004. Epub 2021 Mar 25. Cell Metab. 2021. PMID: 33770509 Free PMC article.
Maternal Exercise-Induced SOD3 Reverses the Deleterious Effects of Maternal High-Fat Diet on Offspring Metabolism Through Stabilization of H3K4me3 and Protection Against WDR82 Carbonylation.
Kusuyama J, Makarewicz NS, Albertson BG, Alves-Wagner AB, Conlin RH, Prince NB, Alves CRR, Ramachandran K, Kozuka C, Xiudong Y, Xia Y, Hirshman MF, Hatta T, Nagatomi R, Nozik ES, Goodyear LJ. Kusuyama J, et al. Among authors: xia y. Diabetes. 2022 Jun 1;71(6):1170-1181. doi: 10.2337/db21-0706. Diabetes. 2022. PMID: 35290440 Free PMC article.
mTOR: a placental growth signaling sensor.
Wen HY, Abbasi S, Kellems RE, Xia Y. Wen HY, et al. Among authors: xia y. Placenta. 2005 Apr;26 Suppl A:S63-9. doi: 10.1016/j.placenta.2005.02.004. Placenta. 2005. PMID: 15837070
A2B adenosine receptor-mediated induction of IL-6 promotes CKD.
Dai Y, Zhang W, Wen J, Zhang Y, Kellems RE, Xia Y. Dai Y, et al. Among authors: xia y. J Am Soc Nephrol. 2011 May;22(5):890-901. doi: 10.1681/ASN.2010080890. Epub 2011 Apr 21. J Am Soc Nephrol. 2011. PMID: 21511827 Free PMC article.
Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.
Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, Kellems RE, Xia Y. Zhang W, et al. Among authors: xia y. Circ Res. 2013 May 24;112(11):1466-78. doi: 10.1161/CIRCRESAHA.111.300166. Epub 2013 Apr 12. Circ Res. 2013. PMID: 23584256 Free PMC article.
Excess LIGHT contributes to placental impairment, increased secretion of vasoactive factors, hypertension, and proteinuria in preeclampsia.
Wang W, Parchim NF, Iriyama T, Luo R, Zhao C, Liu C, Irani RA, Zhang W, Ning C, Zhang Y, Blackwell SC, Chen L, Tao L, Hicks MJ, Kellems RE, Xia Y. Wang W, et al. Among authors: xia y. Hypertension. 2014 Mar;63(3):595-606. doi: 10.1161/HYPERTENSIONAHA.113.02458. Epub 2013 Dec 9. Hypertension. 2014. PMID: 24324043 Free PMC article.
Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia.
Iriyama T, Sun K, Parchim NF, Li J, Zhao C, Song A, Hart LA, Blackwell SC, Sibai BM, Chan LN, Chan TS, Hicks MJ, Blackburn MR, Kellems RE, Xia Y. Iriyama T, et al. Among authors: xia y. Circulation. 2015 Feb 24;131(8):730-41. doi: 10.1161/CIRCULATIONAHA.114.013740. Epub 2014 Dec 23. Circulation. 2015. PMID: 25538227 Free PMC article.
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