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Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.
Hamm J, Sullivan K, Clippinger AJ, Strickland J, Bell S, Bhhatarai B, Blaauboer B, Casey W, Dorman D, Forsby A, Garcia-Reyero N, Gehen S, Graepel R, Hotchkiss J, Lowit A, Matheson J, Reaves E, Scarano L, Sprankle C, Tunkel J, Wilson D, Xia M, Zhu H, Allen D. Hamm J, et al. Among authors: xia m. Toxicol In Vitro. 2017 Jun;41:245-259. doi: 10.1016/j.tiv.2017.01.004. Epub 2017 Jan 6. Toxicol In Vitro. 2017. PMID: 28069485 Free PMC article. Review.
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway.
Huang R, Sakamuru S, Martin MT, Reif DM, Judson RS, Houck KA, Casey W, Hsieh JH, Shockley KR, Ceger P, Fostel J, Witt KL, Tong W, Rotroff DM, Zhao T, Shinn P, Simeonov A, Dix DJ, Austin CP, Kavlock RJ, Tice RR, Xia M. Huang R, et al. Among authors: xia m. Sci Rep. 2014 Jul 11;4:5664. doi: 10.1038/srep05664. Sci Rep. 2014. PMID: 25012808 Free PMC article.
Performance of the BG1Luc ER TA method in a qHTS format.
Ceger P, Allen D, Huang R, Xia M, Casey W. Ceger P, et al. Among authors: xia m. ALTEX. 2015;32(4):287-96. doi: 10.14573/altex.1505121. Epub 2015 Jun 28. ALTEX. 2015. PMID: 26117232 Free PMC article.
Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data.
Kim MT, Huang R, Sedykh A, Wang W, Xia M, Zhu H. Kim MT, et al. Among authors: xia m. Environ Health Perspect. 2016 May;124(5):634-41. doi: 10.1289/ehp.1509763. Epub 2015 Sep 18. Environ Health Perspect. 2016. PMID: 26383846 Free PMC article.
CONCLUSION: Profiling chemical IVIVCs created an opportunity to fully explore the source-to-outcome continuum of modern experimental toxicology using cheminformatics approaches and big data sources. CITATION: Kim MT, Huang R, Sedykh A, Wang W, Xia M, Zhu H. 2016. Me …
CONCLUSION: Profiling chemical IVIVCs created an opportunity to fully explore the source-to-outcome continuum of modern experimental toxicol …
Differential modulation of FXR activity by chlorophacinone and ivermectin analogs.
Hsu CW, Hsieh JH, Huang R, Pijnenburg D, Khuc T, Hamm J, Zhao J, Lynch C, van Beuningen R, Chang X, Houtman R, Xia M. Hsu CW, et al. Among authors: xia m. Toxicol Appl Pharmacol. 2016 Dec 15;313:138-148. doi: 10.1016/j.taap.2016.10.017. Epub 2016 Oct 20. Toxicol Appl Pharmacol. 2016. PMID: 27773686 Free PMC article.
3,348 results