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Topical gel containing phenolic-rich extract from Ipomoea pes-capre leaf (Convolvulaceae) has anti-inflammatory, wound healing, and antiophidic properties.
Xavier-Santos JB, Passos JGR, Gomes JAS, Cruz JVC, Alves JSF, Garcia VB, da Silva RM, Lopes NP, Araujo-Junior RF, Zucolotto SM, Silva-Junior AA, Félix-Silva J, Fernandes-Pedrosa MF. Xavier-Santos JB, et al. Biomed Pharmacother. 2022 May;149:112921. doi: 10.1016/j.biopha.2022.112921. Epub 2022 Apr 7. Biomed Pharmacother. 2022. PMID: 36068780 Free article.
Local anti-inflammatory activity: Topical formulation containing Kalanchoe brasiliensis and Kalanchoe pinnata leaf aqueous extract.
de Araújo ERD, Félix-Silva J, Xavier-Santos JB, Fernandes JM, Guerra GCB, de Araújo AA, Araújo DFS, de Santis Ferreira L, da Silva Júnior AA, Fernandes-Pedrosa MF, Zucolotto SM. de Araújo ERD, et al. Among authors: xavier santos jb. Biomed Pharmacother. 2019 May;113:108721. doi: 10.1016/j.biopha.2019.108721. Epub 2019 Mar 8. Biomed Pharmacother. 2019. PMID: 30856538 Free article.
Inhibition of local effects induced by Bothrops erythromelas snake venom: Assessment of the effectiveness of Brazilian polyvalent bothropic antivenom and aqueous leaf extract of Jatropha gossypiifolia.
Félix-Silva J, Gomes JA, Xavier-Santos JB, Passos JG, Silva-Junior AA, Tambourgi DV, Fernandes-Pedrosa MF. Félix-Silva J, et al. Among authors: xavier santos jb. Toxicon. 2017 Jan;125:74-83. doi: 10.1016/j.toxicon.2016.11.260. Epub 2016 Nov 25. Toxicon. 2017. PMID: 27890774 Free article.
Development of an effective and safe topical anti-inflammatory gel containing Jatropha gossypiifolia leaf extract: Results from a pre-clinical trial in mice.
Xavier-Santos JB, Félix-Silva J, Passos JGR, Gomes JAS, Fernandes JM, Garcia VB, de Araujo-Junior RF, Zucolotto SM, Silva-Junior AA, Fernandes-Pedrosa MF. Xavier-Santos JB, et al. J Ethnopharmacol. 2018 Dec 5;227:268-278. doi: 10.1016/j.jep.2018.09.007. Epub 2018 Sep 6. J Ethnopharmacol. 2018. PMID: 30195567 Free article.
Nanoemulsion containing Jatropha gossypiifolia leaf extract reduces dermonecrosis induced by Bothrops erythromelas venom and accelerates wound closure.
Batista BKDC, Silva JFOD, Passos JGR, Ferreira MRA, Soares LAL, Rocha HAO, Silva-Júnior AA, Xavier-Santos JB, Fernandes-Pedrosa MF. Batista BKDC, et al. Among authors: xavier santos jb. J Ethnopharmacol. 2024 Aug 10;330:118188. doi: 10.1016/j.jep.2024.118188. Epub 2024 Apr 10. J Ethnopharmacol. 2024. PMID: 38608797
Anti-inflammatory, healing and antiophidic potential of Jatropha mollissima (Pohl) Baill. (Euphorbiaceae): From popular use to pharmaceutical formulation in gel.
Passos JGR, Gomes JAS, Xavier-Santos JB, Yamashita FO, Cavalcanti-Cruz JV, Siqueira EMS, Garcia VB, Zucolotto SM, de Araujo-Junior RF, Ferreira LS, Silva-Junior AA, Félix-Silva J, Fernandes-Pedrosa MF. Passos JGR, et al. Among authors: xavier santos jb. Biomed Pharmacother. 2024 Apr;173:116290. doi: 10.1016/j.biopha.2024.116290. Epub 2024 Mar 7. Biomed Pharmacother. 2024. PMID: 38458010 Free article.
Gel formulated with Bryophyllum pinnatum leaf extract promotes skin wound healing in vivo by increasing VEGF expression: A novel potential active ingredient for pharmaceuticals.
Araújo ERD, Xavier-Santos JB, da Silva VC, de Lima JBF, Schlamb J, Fernandes-Pedrosa MF, da Silva Júnior AA, de Araújo Júnior RF, Rathinasabapathy T, Moncada M, Esposito D, Guerra GCB, Zucolotto SM. Araújo ERD, et al. Among authors: xavier santos jb. Front Pharmacol. 2023 Jan 12;13:1104705. doi: 10.3389/fphar.2022.1104705. eCollection 2022. Front Pharmacol. 2023. PMID: 36712663 Free PMC article.