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Reductive carboxylation epigenetically instructs T cell differentiation.
Jaccard A, Wyss T, Maldonado-Pérez N, Rath JA, Bevilacqua A, Peng JJ, Lepez A, Von Gunten C, Franco F, Kao KC, Camviel N, Martín F, Ghesquière B, Migliorini D, Arber C, Romero P, Ho PC, Wenes M. Jaccard A, et al. Among authors: wyss t. Nature. 2023 Sep;621(7980):849-856. doi: 10.1038/s41586-023-06546-y. Epub 2023 Sep 20. Nature. 2023. PMID: 37730993
CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML.
Salomé B, Gomez-Cadena A, Loyon R, Suffiotti M, Salvestrini V, Wyss T, Vanoni G, Ruan DF, Rossi M, Tozzo A, Tentorio P, Bruni E, Riether C, Jacobsen EM, Jandus P, Conrad C, Hoenig M, Schulz A, Michaud K, Della Porta MG, Salvatore S, Ho PC, Gfeller D, Ochsenbein A, Mavilio D, Curti A, Marcenaro E, Steinle A, Horowitz A, Romero P, Trabanelli S, Jandus C. Salomé B, et al. Among authors: wyss t. Blood Adv. 2019 Nov 26;3(22):3674-3687. doi: 10.1182/bloodadvances.2018030478. Blood Adv. 2019. PMID: 31765481 Free PMC article.
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions.
Ercolano G, Gomez-Cadena A, Dumauthioz N, Vanoni G, Kreutzfeldt M, Wyss T, Michalik L, Loyon R, Ianaro A, Ho PC, Borg C, Kopf M, Merkler D, Krebs P, Romero P, Trabanelli S, Jandus C. Ercolano G, et al. Among authors: wyss t. Nat Commun. 2021 May 5;12(1):2538. doi: 10.1038/s41467-021-22764-2. Nat Commun. 2021. PMID: 33953160 Free PMC article.
The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function.
Wenes M, Jaccard A, Wyss T, Maldonado-Pérez N, Teoh ST, Lepez A, Renaud F, Franco F, Waridel P, Yacoub Maroun C, Tschumi B, Dumauthioz N, Zhang L, Donda A, Martín F, Migliorini D, Lunt SY, Ho PC, Romero P. Wenes M, et al. Among authors: wyss t. Cell Metab. 2022 May 3;34(5):731-746.e9. doi: 10.1016/j.cmet.2022.03.013. Epub 2022 Apr 21. Cell Metab. 2022. PMID: 35452600 Free PMC article.
Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion.
Tillé L, Cropp D, Charmoy M, Reichenbach P, Andreatta M, Wyss T, Bodley G, Crespo I, Nassiri S, Lourenco J, Leblond MM, Lopez-Rodriguez C, Speiser DE, Coukos G, Irving M, Carmona SJ, Held W, Verdeil G. Tillé L, et al. Among authors: wyss t. Nat Immunol. 2023 Oct;24(10):1645-1653. doi: 10.1038/s41590-023-01614-x. Epub 2023 Sep 14. Nat Immunol. 2023. PMID: 37709986
Quantitative and qualitative impairments in dendritic cell subsets of patients with ovarian or prostate cancer.
Mastelic-Gavillet B, Sarivalasis A, Lozano LE, Wyss T, Inoges S, de Vries IJM, Dartiguenave F, Jichlinski P, Derrè L, Coukos G, Melero I, Harari A, Romero P, Viganó S, Kandalaft LE. Mastelic-Gavillet B, et al. Among authors: wyss t. Eur J Cancer. 2020 Aug;135:173-182. doi: 10.1016/j.ejca.2020.04.036. Epub 2020 Jun 23. Eur J Cancer. 2020. PMID: 32590296 Free article.
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer.
Cachot A, Bilous M, Liu YC, Li X, Saillard M, Cenerenti M, Rockinger GA, Wyss T, Guillaume P, Schmidt J, Genolet R, Ercolano G, Protti MP, Reith W, Ioannidou K, de Leval L, Trapani JA, Coukos G, Harari A, Speiser DE, Mathis A, Gfeller D, Altug H, Romero P, Jandus C. Cachot A, et al. Among authors: wyss t. Sci Adv. 2021 Feb 26;7(9):eabe3348. doi: 10.1126/sciadv.abe3348. Print 2021 Feb. Sci Adv. 2021. PMID: 33637530 Free PMC article.
CD40 Agonist Targeted to Fibroblast Activation Protein α Synergizes with Radiotherapy in Murine HPV-Positive Head and Neck Tumors.
Labiano S, Roh V, Godfroid C, Hiou-Feige A, Romero J, Sum E, Rapp M, Boivin G, Wyss T, Simon C, Bourhis J, Umaña P, Trumpfheller C, Tolstonog GV, Vozenin MC, Romero P. Labiano S, et al. Among authors: wyss t. Clin Cancer Res. 2021 Jul 15;27(14):4054-4065. doi: 10.1158/1078-0432.CCR-20-4717. Epub 2021 Apr 26. Clin Cancer Res. 2021. PMID: 33903200
Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures.
Fleig S, Kapanadze T, Bernier-Latmani J, Lill JK, Wyss T, Gamrekelashvili J, Kijas D, Liu B, Hüsing AM, Bovay E, Jirmo AC, Halle S, Ricke-Hoch M, Adams RH, Engel DR, von Vietinghoff S, Förster R, Hilfiker-Kleiner D, Haller H, Petrova TV, Limbourg FP. Fleig S, et al. Among authors: wyss t. Nat Commun. 2022 Apr 19;13(1):2022. doi: 10.1038/s41467-022-29701-x. Nat Commun. 2022. PMID: 35440634 Free PMC article.
167 results