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TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.
Scotto Rosato A, Krogsaeter EK, Jaślan D, Abrahamian C, Montefusco S, Soldati C, Spix B, Pizzo MT, Grieco G, Böck J, Wyatt A, Wünkhaus D, Passon M, Stieglitz M, Keller M, Hermey G, Markmann S, Gruber-Schoffnegger D, Cotman S, Johannes L, Crusius D, Boehm U, Wahl-Schott C, Biel M, Bracher F, De Leonibus E, Polishchuk E, Medina DL, Paquet D, Grimm C. Scotto Rosato A, et al. Among authors: wyatt a. EMBO Mol Med. 2022 Sep 7;14(9):e15377. doi: 10.15252/emmm.202115377. Epub 2022 Aug 5. EMBO Mol Med. 2022. PMID: 35929194 Free PMC article.
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice.
Spix B, Butz ES, Chen CC, Rosato AS, Tang R, Jeridi A, Kudrina V, Plesch E, Wartenberg P, Arlt E, Briukhovetska D, Ansari M, Günsel GG, Conlon TM, Wyatt A, Wetzel S, Teupser D, Holdt LM, Ectors F, Boekhoff I, Boehm U, García-Añoveros J, Saftig P, Giera M, Kobold S, Schiller HB, Zierler S, Gudermann T, Wahl-Schott C, Bracher F, Yildirim AÖ, Biel M, Grimm C. Spix B, et al. Among authors: wyatt a. Nat Commun. 2022 Jan 14;13(1):318. doi: 10.1038/s41467-021-27860-x. Nat Commun. 2022. PMID: 35031603 Free PMC article.
Whole-body analysis of TRPML3 (MCOLN3) expression using a GFP-reporter mouse model reveals widespread expression in secretory cells and endocrine glands.
Spix B, Castiglioni AJ, Remis NN, Flores EN, Wartenberg P, Wyatt A, Boehm U, Gudermann T, Biel M, García-Añoveros J, Grimm C. Spix B, et al. Among authors: wyatt a. PLoS One. 2022 Dec 15;17(12):e0278848. doi: 10.1371/journal.pone.0278848. eCollection 2022. PLoS One. 2022. PMID: 36520788 Free PMC article.
Ovulation is triggered by a cyclical modulation of gonadotropes into a hyperexcitable state.
Götz V, Qiao S, Das D, Wartenberg P, Wyatt A, Wahl V, Gamayun I, Alasmi S, Fecher-Trost C, Meyer MR, Rad R, Kaltenbacher T, Kattler K, Lipp P, Becherer U, Mollard P, Candlish M, Boehm U. Götz V, et al. Among authors: wyatt a. Cell Rep. 2023 Jun 27;42(6):112543. doi: 10.1016/j.celrep.2023.112543. Epub 2023 May 23. Cell Rep. 2023. PMID: 37224016 Free article.
387 results