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Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.
Ma L, Sahu SK, Cano M, Kuppuswamy V, Bajwa J, McPhatter J, Pine A, Meizlish M, Goshua G, Chang CH, Zhang H, Price C, Bahel P, Rinder H, Lei T, Day A, Reynolds D, Wu X, Schriefer R, Rauseo AM, Goss CW, O'Halloran JA, Presti RM, Kim AH, Gelman AE, Cruz CD, Lee AI, Mudd P, Chun HJ, Atkinson JP, Kulkarni HS. Ma L, et al. Among authors: wu x. bioRxiv [Preprint]. 2021 Feb 23:2021.02.22.432177. doi: 10.1101/2021.02.22.432177. bioRxiv. 2021. PMID: 33655244 Free PMC article. Updated. Preprint.
The beneficial and pathogenic roles of complement in COVID-19.
Kim AHJ, Wu X, Atkinson JP. Kim AHJ, et al. Among authors: wu x. Cleve Clin J Med. 2020 Oct 28:10.3949/ccjm.87a.ccc065. doi: 10.3949/ccjm.87a.ccc065. Online ahead of print. Cleve Clin J Med. 2020. PMID: 33115882 Free PMC article.
Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury.
Sahu SK, Ozantürk AN, Kulkarni DH, Ma L, Barve RA, Dannull L, Lu A, Starick M, McPhatter J, Garnica L, Sanfillipo-Burchman M, Kunen J, Wu X, Gelman AE, Brody SL, Atkinson JP, Kulkarni HS. Sahu SK, et al. Among authors: wu x. Sci Immunol. 2023 Feb 3;8(80):eabp9547. doi: 10.1126/sciimmunol.abp9547. Epub 2023 Feb 3. Sci Immunol. 2023. PMID: 36735773 Free PMC article.
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