Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy.
Thannickal TC, John J, Shan L, Swaab DF, Wu MF, Ramanathan L, McGregor R, Chew KT, Cornford M, Yamanaka A, Inutsuka A, Fronczek R, Lammers GJ, Worley PF, Siegel JM.
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Sci Transl Med. 2018 Jun 27;10(447):eaao4953. doi: 10.1126/scitranslmed.aao4953.
Sci Transl Med. 2018.
PMID: 29950444
Free PMC article.