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Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease.
Liu CC, Wang N, Chen Y, Inoue Y, Shue F, Ren Y, Wang M, Qiao W, Ikezu TC, Li Z, Zhao J, Martens Y, Doss SV, Rosenberg CL, Jeevaratnam S, Jia L, Raulin AC, Qi F, Zhu Y, Alnobani A, Knight J, Chen Y, Linares C, Kurti A, Fryer JD, Zhang B, Wu LJ, Kim BYS, Bu G. Liu CC, et al. Among authors: wu lj. Nat Immunol. 2023 Nov;24(11):1854-1866. doi: 10.1038/s41590-023-01640-9. Epub 2023 Oct 19. Nat Immunol. 2023. PMID: 37857825
Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia.
Zhao N, Qiao W, Li F, Ren Y, Zheng J, Martens YA, Wang X, Li L, Liu CC, Chen K, Zhu Y, Ikezu TC, Li Z, Meneses AD, Jin Y, Knight JA, Chen Y, Bastea L, Linares C, Sonustun B, Job L, Smith ML, Xie M, Liu YU, Umpierre AD, Haruwaka K, Quicksall ZS, Storz P, Asmann YW, Wu LJ, Bu G. Zhao N, et al. Among authors: wu lj. J Exp Med. 2022 Dec 5;219(12):e20212479. doi: 10.1084/jem.20212479. Epub 2022 Sep 15. J Exp Med. 2022. PMID: 36107206 Free PMC article.
TREM2 mediates MHCII-associated CD4+ T-cell response against gliomas.
Zheng J, Wang L, Zhao S, Zhang W, Chang Y, Bosco DB, Huang T, Dheer A, Gao S, Xu S, Ayasoufi K, Al-Kharboosh R, Qi F, Xie M, Johnson AJ, Dong H, Quiñones-Hinojosa A, Wu LJ. Zheng J, et al. Among authors: wu lj. Neuro Oncol. 2024 May 3;26(5):811-825. doi: 10.1093/neuonc/noad214. Neuro Oncol. 2024. PMID: 37941134
The Emerging Role of Microglia in Neuromyelitis Optica.
Chen T, Bosco DB, Ying Y, Tian DS, Wu LJ. Chen T, et al. Among authors: wu lj. Front Immunol. 2021 Feb 19;12:616301. doi: 10.3389/fimmu.2021.616301. eCollection 2021. Front Immunol. 2021. PMID: 33679755 Free PMC article. Review.
Microglial TREM2 in amyotrophic lateral sclerosis.
Xie M, Zhao S, Bosco DB, Nguyen A, Wu LJ. Xie M, et al. Among authors: wu lj. Dev Neurobiol. 2022 Jan;82(1):125-137. doi: 10.1002/dneu.22864. Epub 2021 Dec 18. Dev Neurobiol. 2022. PMID: 34874625 Free PMC article. Review.
929 results