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Antibody targeting of E3 ubiquitin ligases for receptor degradation.
Marei H, Tsai WK, Kee YS, Ruiz K, He J, Cox C, Sun T, Penikalapati S, Dwivedi P, Choi M, Kan D, Saenz-Lopez P, Dorighi K, Zhang P, Kschonsak YT, Kljavin N, Amin D, Kim I, Mancini AG, Nguyen T, Wang C, Janezic E, Doan A, Mai E, Xi H, Gu C, Heinlein M, Biehs B, Wu J, Lehoux I, Harris S, Comps-Agrar L, Seshasayee D, de Sauvage FJ, Grimmer M, Li J, Agard NJ, de Sousa E Melo F. Marei H, et al. Among authors: wu j. Nature. 2022 Oct;610(7930):182-189. doi: 10.1038/s41586-022-05235-6. Epub 2022 Sep 21. Nature. 2022. PMID: 36131013 Free PMC article.
Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development.
Mai E, Chan J, Goon L, Ego BK, Bevers J, Wong T, Wong M, Corpuz R, Xi H, Wu J, Schneider K, Seshasayee D, Grimbaldeston M, Nakamura G, Indjeian VB, van Lookeren Campagne M, Loyet KM, Comps-Agrar L. Mai E, et al. Among authors: wu j. J Transl Med. 2021 Dec 20;19(1):517. doi: 10.1186/s12967-021-03189-3. J Transl Med. 2021. PMID: 34930320 Free PMC article.
Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies.
Goldstein LD, Chen YJ, Wu J, Chaudhuri S, Hsiao YC, Schneider K, Hoi KH, Lin Z, Guerrero S, Jaiswal BS, Stinson J, Antony A, Pahuja KB, Seshasayee D, Modrusan Z, Hötzel I, Seshagiri S. Goldstein LD, et al. Among authors: wu j. Commun Biol. 2019 Aug 9;2:304. doi: 10.1038/s42003-019-0551-y. eCollection 2019. Commun Biol. 2019. PMID: 31428692 Free PMC article.
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis.
Sun T, Huang Z, Liang WC, Yin J, Lin WY, Wu J, Vernes JM, Lutman J, Caplazi P, Jeet S, Wong T, Wong M, DePianto DJ, Morshead KB, Sun KH, Modrusan Z, Vander Heiden JA, Abbas AR, Zhang H, Xu M, N'Diaye EN, Roose-Girma M, Wolters PJ, Yadav R, Sukumaran S, Ghilardi N, Corpuz R, Emson C, Meng YG, Ramalingam TR, Lupardus P, Brightbill HD, Seshasayee D, Wu Y, Arron JR. Sun T, et al. Among authors: wu y, wu j. Sci Transl Med. 2021 Aug 4;13(605):eabe0407. doi: 10.1126/scitranslmed.abe0407. Sci Transl Med. 2021. PMID: 34349032
Association between bronchiectasis exacerbations and longitudinal changes in FEV1 in patients from the US Bronchiectasis and NTM Research Registry.
Aksamit TR, Lapinel NC, Choate R, Feliciano J, Winthrop KL, Schmid A, Wu J, Fucile S, Metersky ML; Bronchiectasis and NTM Research Registry Investigators. Aksamit TR, et al. Among authors: wu j. Respir Med. 2024 May 9:107660. doi: 10.1016/j.rmed.2024.107660. Online ahead of print. Respir Med. 2024. PMID: 38734153
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