Wu H - Search Results

1

Direct enzymatic sequencing of 5-methylcytosine at single-base resolution.

Wang T, Fowler JM, Liu L, Loo CE, Luo M, Schutsky EK, Berríos KN, DeNizio JE, Dvorak A, Downey N, Montermoso S, Pingul BY, Nasrallah M, Gosal WS, Wu H, Kohli RM. Wang T, et al. Among authors: wu h. Nat Chem Biol. 2023 Aug;19(8):1004-1012. doi: 10.1038/s41589-023-01318-1. Epub 2023 Jun 15. Nat Chem Biol. 2023. PMID: 37322153 Free PMC article.

2

Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase.

Schutsky EK, DeNizio JE, Hu P, Liu MY, Nabel CS, Fabyanic EB, Hwang Y, Bushman FD, Wu H, Kohli RM. Schutsky EK, et al. Among authors: wu h. Nat Biotechnol. 2018 Oct 8:10.1038/nbt.4204. doi: 10.1038/nbt.4204. Online ahead of print. Nat Biotechnol. 2018. PMID: 30295673 Free PMC article.

3

Bisulfite-Free Sequencing of 5-Hydroxymethylcytosine with APOBEC-Coupled Epigenetic Sequencing (ACE-Seq).

Wang T, Luo M, Berrios KN, Schutsky EK, Wu H, Kohli RM. Wang T, et al. Among authors: wu h. Methods Mol Biol. 2021;2198:349-367. doi: 10.1007/978-1-0716-0876-0_27. Methods Mol Biol. 2021. PMID: 32822044

4

Massively parallel and time-resolved RNA sequencing in single cells with scNT-seq.

Qiu Q, Hu P, Qiu X, Govek KW, Cámara PG, Wu H. Qiu Q, et al. Among authors: wu h. Nat Methods. 2020 Oct;17(10):991-1001. doi: 10.1038/s41592-020-0935-4. Epub 2020 Aug 31. Nat Methods. 2020. PMID: 32868927 Free PMC article.

5

Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects.

Fabyanic EB, Hu P, Qiu Q, Berríos KN, Connolly DR, Wang T, Flournoy J, Zhou Z, Kohli RM, Wu H. Fabyanic EB, et al. Among authors: wu h. Nat Biotechnol. 2023 Aug 28. doi: 10.1038/s41587-023-01909-2. Online ahead of print. Nat Biotechnol. 2023. PMID: 37640946

6

Dissecting Cell-Type Composition and Activity-Dependent Transcriptional State in Mammalian Brains by Massively Parallel Single-Nucleus RNA-Seq.

Hu P, Fabyanic E, Kwon DY, Tang S, Zhou Z, Wu H. Hu P, et al. Among authors: wu h. Mol Cell. 2017 Dec 7;68(5):1006-1015.e7. doi: 10.1016/j.molcel.2017.11.017. Mol Cell. 2017. PMID: 29220646 Free PMC article.

7

Integrating Single-Cell Methylome and Transcriptome Data with MAPLE.

Uzun Y, Wu H, Tan K. Uzun Y, et al. Among authors: wu h. Methods Mol Biol. 2023;2624:43-54. doi: 10.1007/978-1-0716-2962-8_4. Methods Mol Biol. 2023. PMID: 36723808

8

5-hydroxymethylcytosines regulate gene expression as a passive DNA demethylation resisting epigenetic mark in proliferative somatic cells.

Wei A, Zhang H, Qiu Q, Fabyanic EB, Hu P, Wu H. Wei A, et al. Among authors: wu h. bioRxiv [Preprint]. 2023 Sep 27:2023.09.26.559662. doi: 10.1101/2023.09.26.559662. bioRxiv. 2023. PMID: 37808741 Free PMC article. Preprint.

9

Neuronal Yin Yang1 in the prefrontal cortex regulates transcriptional and behavioral responses to chronic stress in mice.

Kwon DY, Xu B, Hu P, Zhao YT, Beagan JA, Nofziger JH, Cui Y, Phillips-Cremins JE, Blendy JA, Wu H, Zhou Z. Kwon DY, et al. Among authors: wu h. Nat Commun. 2022 Jan 10;13(1):55. doi: 10.1038/s41467-021-27571-3. Nat Commun. 2022. PMID: 35013139 Free PMC article.

10

Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome.

Malachowski T, Chandradoss KR, Boya R, Zhou L, Cook AL, Su C, Pham K, Haws SA, Kim JH, Ryu HS, Ge C, Luppino JM, Nguyen SC, Titus KR, Gong W, Wallace O, Joyce EF, Wu H, Rojas LA, Phillips-Cremins JE. Malachowski T, et al. Among authors: wu h. Cell. 2023 Dec 21;186(26):5840-5858.e36. doi: 10.1016/j.cell.2023.11.019. Cell. 2023. PMID: 38134876 Free article.

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