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Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response.
Huo Y, Guo X, Li H, Wang H, Zhang W, Wang Y, Zhou H, Gao Z, Telang S, Chesney J, Chen YE, Ye J, Chapkin RS, Wu C. Huo Y, et al. Among authors: wu c. J Biol Chem. 2010 Feb 5;285(6):3713-3721. doi: 10.1074/jbc.M109.058446. Epub 2009 Nov 30. J Biol Chem. 2010. PMID: 19948719 Free PMC article.
Endothelial PFKFB3 plays a critical role in angiogenesis.
Xu Y, An X, Guo X, Habtetsion TG, Wang Y, Xu X, Kandala S, Li Q, Li H, Zhang C, Caldwell RB, Fulton DJ, Su Y, Hoda MN, Zhou G, Wu C, Huo Y. Xu Y, et al. Among authors: wu c. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1231-9. doi: 10.1161/ATVBAHA.113.303041. Epub 2014 Apr 3. Arterioscler Thromb Vasc Biol. 2014. PMID: 24700124 Free PMC article.
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