Wright GD - Search Results

1

Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7.

Bergstrom A, Katko A, Adkins Z, Hill J, Cheng Z, Burnett M, Yang H, Aitha M, Mehaffey MR, Brodbelt JS, Tehrani KHME, Martin NI, Bonomo RA, Page RC, Tierney DL, Fast W, Wright GD, Crowder MW. Bergstrom A, et al. Among authors: wright gd. ACS Infect Dis. 2018 Feb 9;4(2):135-145. doi: 10.1021/acsinfecdis.7b00106. Epub 2017 Nov 9. ACS Infect Dis. 2018. PMID: 29091730 Free PMC article.

2

Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance.

King AM, Reid-Yu SA, Wang W, King DT, De Pascale G, Strynadka NC, Walsh TR, Coombes BK, Wright GD. King AM, et al. Among authors: wright gd. Nature. 2014 Jun 26;510(7506):503-6. doi: 10.1038/nature13445. Nature. 2014. PMID: 24965651 Free PMC article.

3

Total Synthesis and Activity of the Metallo-β-lactamase Inhibitor Aspergillomarasmine A.

Koteva K, King AM, Capretta A, Wright GD. Koteva K, et al. Among authors: wright gd. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2210-2. doi: 10.1002/anie.201510057. Epub 2015 Dec 28. Angew Chem Int Ed Engl. 2016. PMID: 26709849

4

Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins.

King AM, King DT, French S, Brouillette E, Asli A, Alexander JA, Vuckovic M, Maiti SN, Parr TR Jr, Brown ED, Malouin F, Strynadka NC, Wright GD. King AM, et al. Among authors: wright gd. ACS Chem Biol. 2016 Apr 15;11(4):864-8. doi: 10.1021/acschembio.5b00944. Epub 2016 Jan 14. ACS Chem Biol. 2016. PMID: 26731698

5

Solving the Antibiotic Crisis.

Wright GD. Wright GD. ACS Infect Dis. 2015 Feb 13;1(2):80-4. doi: 10.1021/id500052s. Epub 2015 Jan 15. ACS Infect Dis. 2015. PMID: 27622298

6

Molecular Mechanism of Avibactam-Mediated β-Lactamase Inhibition.

King DT, King AM, Lal SM, Wright GD, Strynadka NC. King DT, et al. Among authors: wright gd. ACS Infect Dis. 2015 Apr 10;1(4):175-84. doi: 10.1021/acsinfecdis.5b00007. Epub 2015 Feb 11. ACS Infect Dis. 2015. PMID: 27622530

7

Alternative Pathway to a Glycopeptide-Resistant Cell Wall in the Balhimycin Producer Amycolatopsis balhimycina.

Frasch HJ, Kalan L, Kilian R, Martin T, Wright GD, Stegmann E. Frasch HJ, et al. Among authors: wright gd. ACS Infect Dis. 2015 Jun 12;1(6):243-52. doi: 10.1021/acsinfecdis.5b00011. Epub 2015 May 15. ACS Infect Dis. 2015. PMID: 27622740

8

Zinc Chelation by a Small-Molecule Adjuvant Potentiates Meropenem Activity in Vivo against NDM-1-Producing Klebsiella pneumoniae.

Falconer SB, Reid-Yu SA, King AM, Gehrke SS, Wang W, Britten JF, Coombes BK, Wright GD, Brown ED. Falconer SB, et al. Among authors: wright gd. ACS Infect Dis. 2015 Nov 13;1(11):533-43. doi: 10.1021/acsinfecdis.5b00033. Epub 2015 May 26. ACS Infect Dis. 2015. PMID: 27623408

9

Total Synthesis of Aspergillomarasmine A and Related Compounds: A Sulfamidate Approach Enables Exploration of Structure-Activity Relationships.

Albu SA, Koteva K, King AM, Al-Karmi S, Wright GD, Capretta A. Albu SA, et al. Among authors: wright gd. Angew Chem Int Ed Engl. 2016 Oct 10;55(42):13259-13262. doi: 10.1002/anie.201606657. Angew Chem Int Ed Engl. 2016. PMID: 27633338

10

How To Make a Glycopeptide: A Synthetic Biology Approach To Expand Antibiotic Chemical Diversity.

Yim G, Wang W, Thaker MN, Tan S, Wright GD. Yim G, et al. Among authors: wright gd. ACS Infect Dis. 2016 Sep 9;2(9):642-650. doi: 10.1021/acsinfecdis.6b00105. Epub 2016 Aug 5. ACS Infect Dis. 2016. PMID: 27759388

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