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Optimized monoclonal antibody treatment against ELTD1 for GBM in a G55 xenograft mouse model.
Zalles M, Smith N, Ziegler J, Saunders D, Remerowski S, Thomas L, Gulej R, Mamedova N, Lerner M, Fung KM, Chung J, Hwang K, Jin J, Wiley G, Brown C, Battiste J, Wren JD, Towner RA. Zalles M, et al. Among authors: wren jd. J Cell Mol Med. 2020 Jan;24(2):1738-1749. doi: 10.1111/jcmm.14867. Epub 2019 Dec 21. J Cell Mol Med. 2020. PMID: 31863639 Free PMC article.
ELTD1, a potential new biomarker for gliomas.
Towner RA, Jensen RL, Colman H, Vaillant B, Smith N, Casteel R, Saunders D, Gillespie DL, Silasi-Mansat R, Lupu F, Giles CB, Wren JD. Towner RA, et al. Among authors: wren jd. Neurosurgery. 2013 Jan;72(1):77-90; discussion 91. doi: 10.1227/NEU.0b013e318276b29d. Neurosurgery. 2013. PMID: 23096411 Free PMC article.
Experimental validation of 5 in-silico predicted glioma biomarkers.
Towner RA, Jensen RL, Vaillant B, Colman H, Saunders D, Giles CB, Wren JD. Towner RA, et al. Among authors: wren jd. Neuro Oncol. 2013 Dec;15(12):1625-34. doi: 10.1093/neuonc/not124. Epub 2013 Oct 24. Neuro Oncol. 2013. PMID: 24158112 Free PMC article.
ELTD1, an effective anti-angiogenic target for gliomas: preclinical assessment in mouse GL261 and human G55 xenograft glioma models.
Ziegler J, Pody R, Coutinho de Souza P, Evans B, Saunders D, Smith N, Mallory S, Njoku C, Dong Y, Chen H, Dong J, Lerner M, Mian O, Tummala S, Battiste J, Fung KM, Wren JD, Towner RA. Ziegler J, et al. Among authors: wren jd. Neuro Oncol. 2017 Feb 1;19(2):175-185. doi: 10.1093/neuonc/now147. Neuro Oncol. 2017. PMID: 27416955 Free PMC article.
Homozygous Expression of Mutant ELOVL4 Leads to Seizures and Death in a Novel Animal Model of Very Long-Chain Fatty Acid Deficiency.
Hopiavuori BR, Deák F, Wilkerson JL, Brush RS, Rocha-Hopiavuori NA, Hopiavuori AR, Ozan KG, Sullivan MT, Wren JD, Georgescu C, Szweda L, Awasthi V, Towner R, Sherry DM, Anderson RE, Agbaga MP. Hopiavuori BR, et al. Among authors: wren jd. Mol Neurobiol. 2018 Feb;55(2):1795-1813. doi: 10.1007/s12035-017-0824-8. Epub 2017 Nov 22. Mol Neurobiol. 2018. PMID: 29168048 Free PMC article.
OKN-007 Increases temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth.
Towner RA, Smith N, Saunders D, Brown CA, Cai X, Ziegler J, Mallory S, Dozmorov MG, Coutinho De Souza P, Wiley G, Kim K, Kang S, Kong DS, Kim YT, Fung KM, Wren JD, Battiste J. Towner RA, et al. Among authors: wren jd. Transl Oncol. 2019 Feb;12(2):320-335. doi: 10.1016/j.tranon.2018.10.002. Epub 2018 Nov 20. Transl Oncol. 2019. PMID: 30468988 Free PMC article.
223 results