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Elevated cyclic-AMP represses expression of exchange protein activated by cAMP (EPAC1) by inhibiting YAP-TEAD activity and HDAC-mediated histone deacetylation.
Ebrahimighaei R, McNeill MC, Smith SA, Wray JP, Ford KL, Newby AC, Bond M. Ebrahimighaei R, et al. Among authors: wray jp. Biochim Biophys Acta Mol Cell Res. 2019 Oct;1866(10):1634-1649. doi: 10.1016/j.bbamcr.2019.06.013. Epub 2019 Jun 28. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 31255721 Free article.
A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Böiers C, Richardson SE, Laycock E, Zriwil A, Turati VA, Brown J, Wray JP, Wang D, James C, Herrero J, Sitnicka E, Karlsson S, Smith AJH, Jacobsen SEW, Enver T. Böiers C, et al. Among authors: wray jp. Dev Cell. 2018 Feb 5;44(3):362-377.e7. doi: 10.1016/j.devcel.2017.12.005. Epub 2017 Dec 28. Dev Cell. 2018. PMID: 29290585 Free PMC article.
The ground state of embryonic stem cell self-renewal.
Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, Cohen P, Smith A. Ying QL, et al. Nature. 2008 May 22;453(7194):519-23. doi: 10.1038/nature06968. Nature. 2008. PMID: 18497825 Free PMC article.
Nanog is the gateway to the pluripotent ground state.
Silva J, Nichols J, Theunissen TW, Guo G, van Oosten AL, Barrandon O, Wray J, Yamanaka S, Chambers I, Smith A. Silva J, et al. Cell. 2009 Aug 21;138(4):722-37. doi: 10.1016/j.cell.2009.07.039. Cell. 2009. PMID: 19703398 Free PMC article.
WNTing embryonic stem cells.
Wray J, Hartmann C. Wray J, et al. Trends Cell Biol. 2012 Mar;22(3):159-68. doi: 10.1016/j.tcb.2011.11.004. Epub 2011 Dec 22. Trends Cell Biol. 2012. PMID: 22196214 Review.
Generation and trapping of a mesoderm biased state of human pluripotency.
Stavish D, Böiers C, Price C, Frith TJR, Halliwell J, Saldaña-Guerrero I, Wray J, Brown J, Carr J, James C, Barbaric I, Andrews PW, Enver T. Stavish D, et al. Nat Commun. 2020 Oct 5;11(1):4989. doi: 10.1038/s41467-020-18727-8. Nat Commun. 2020. PMID: 33020476 Free PMC article.
15 results