Woodworth L - Search Results

1

RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis.

Zelic M, Pontarelli F, Woodworth L, Zhu C, Mahan A, Ren Y, LaMorte M, Gruber R, Keane A, Loring P, Guo L, Xia TH, Zhang B, Orning P, Lien E, Degterev A, Hammond T, Ofengeim D. Zelic M, et al. Among authors: woodworth l. Cell Rep. 2021 May 11;35(6):109112. doi: 10.1016/j.celrep.2021.109112. Cell Rep. 2021. PMID: 33979622 Free PMC article.

2

CSF1R signaling is a regulator of pathogenesis in progressive MS.

Hagan N, Kane JL, Grover D, Woodworth L, Madore C, Saleh J, Sancho J, Liu J, Li Y, Proto J, Zelic M, Mahan A, Kothe M, Scholte AA, Fitzgerald M, Gisevius B, Haghikia A, Butovsky O, Ofengeim D. Hagan N, et al. Among authors: woodworth l. Cell Death Dis. 2020 Oct 23;11(10):904. doi: 10.1038/s41419-020-03084-7. Cell Death Dis. 2020. PMID: 33097690 Free PMC article.

3

Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation.

Jafari M, Schumacher AM, Snaidero N, Ullrich Gavilanes EM, Neziraj T, Kocsis-Jutka V, Engels D, Jürgens T, Wagner I, Weidinger JDF, Schmidt SS, Beltrán E, Hagan N, Woodworth L, Ofengeim D, Gans J, Wolf F, Kreutzfeldt M, Portugues R, Merkler D, Misgeld T, Kerschensteiner M. Jafari M, et al. Among authors: woodworth l. Nat Neurosci. 2021 Mar;24(3):355-367. doi: 10.1038/s41593-020-00780-7. Epub 2021 Jan 25. Nat Neurosci. 2021. PMID: 33495636

4

Gene transfer to the CNS is efficacious in immune-primed mice harboring physiologically relevant titers of anti-AAV antibodies.

Treleaven CM, Tamsett TJ, Bu J, Fidler JA, Sardi SP, Hurlbut GD, Woodworth LA, Cheng SH, Passini MA, Shihabuddin LS, Dodge JC. Treleaven CM, et al. Mol Ther. 2012 Sep;20(9):1713-23. doi: 10.1038/mt.2012.114. Epub 2012 Jun 26. Mol Ther. 2012. PMID: 22735381 Free PMC article.

5

Preexisting immunity and low expression in primates highlight translational challenges for liver-directed AAV8-mediated gene therapy.

Hurlbut GD, Ziegler RJ, Nietupski JB, Foley JW, Woodworth LA, Meyers E, Bercury SD, Pande NN, Souza DW, Bree MP, Lukason MJ, Marshall J, Cheng SH, Scheule RK. Hurlbut GD, et al. Mol Ther. 2010 Nov;18(11):1983-94. doi: 10.1038/mt.2010.175. Epub 2010 Aug 24. Mol Ther. 2010. PMID: 20736932 Free PMC article.

6

Potentiation of gene transfer to the mouse lung by complexes of adenovirus vector and polycations improves therapeutic potential.

Kaplan JM, Pennington SE, St George JA, Woodworth LA, Fasbender A, Marshall J, Cheng SH, Wadsworth SC, Gregory RJ, Smith AE. Kaplan JM, et al. Among authors: woodworth la. Hum Gene Ther. 1998 Jul 1;9(10):1469-79. doi: 10.1089/hum.1998.9.10-1469. Hum Gene Ther. 1998. PMID: 9681418

7

Cytotoxic T lymphocyte responses to transgene product, not adeno-associated viral capsid protein, limit transgene expression in mice.

Siders WM, Shields J, Kaplan J, Lukason M, Woodworth L, Wadsworth S, Scaria A. Siders WM, et al. Among authors: woodworth l. Hum Gene Ther. 2009 Jan;20(1):11-20. doi: 10.1089/hum.2008.055. Hum Gene Ther. 2009. PMID: 18828728 Free PMC article.

8

Allogeneic mesenchymal stem cells do not protect NZBxNZW F1 mice from developing lupus disease.

Youd M, Blickarz C, Woodworth L, Touzjian T, Edling A, Tedstone J, Ruzek M, Tubo R, Kaplan J, Lodie T. Youd M, et al. Among authors: woodworth l. Clin Exp Immunol. 2010 Jul 1;161(1):176-86. doi: 10.1111/j.1365-2249.2010.04158.x. Epub 2010 Apr 29. Clin Exp Immunol. 2010. PMID: 20456409 Free PMC article.

9

Induction of antitumor immunity with dendritic cells transduced with adenovirus vector-encoding endogenous tumor-associated antigens.

Kaplan JM, Yu Q, Piraino ST, Pennington SE, Shankara S, Woodworth LA, Roberts BL. Kaplan JM, et al. Among authors: woodworth la. J Immunol. 1999 Jul 15;163(2):699-707. J Immunol. 1999. PMID: 10395660

10

Therapeutic benefit of treatment with anti-thymocyte globulin and latent TGF-beta1 in the MRL/lpr lupus mouse model.

Kaplan J, Woodworth L, Smith K, Coco J, Vitsky A, McPherson J. Kaplan J, et al. Among authors: woodworth l. Lupus. 2008 Sep;17(9):822-31. doi: 10.1177/0961203308091635. Lupus. 2008. PMID: 18755864

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