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Dysregulated naive B cells and de novo autoreactivity in severe COVID-19.
Woodruff MC, Ramonell RP, Haddad NS, Anam FA, Rudolph ME, Walker TA, Truong AD, Dixit AN, Han JE, Cabrera-Mora M, Runnstrom MC, Bugrovsky R, Hom J, Connolly EC, Albizua I, Javia V, Cashman KS, Nguyen DC, Kyu S, Singh Saini A, Piazza M, Tipton CM, Khosroshahi A, Gibson G, Martin GS, Maier CL, Esper A, Jenks SA, Lee FE, Sanz I. Woodruff MC, et al. Nature. 2022 Nov;611(7934):139-147. doi: 10.1038/s41586-022-05273-0. Epub 2022 Aug 31. Nature. 2022. PMID: 36044993 Free PMC article.
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.
Jenks SA, Cashman KS, Zumaquero E, Marigorta UM, Patel AV, Wang X, Tomar D, Woodruff MC, Simon Z, Bugrovsky R, Blalock EL, Scharer CD, Tipton CM, Wei C, Lim SS, Petri M, Niewold TB, Anolik JH, Gibson G, Lee FE, Boss JM, Lund FE, Sanz I. Jenks SA, et al. Among authors: woodruff mc. Immunity. 2018 Oct 16;49(4):725-739.e6. doi: 10.1016/j.immuni.2018.08.015. Epub 2018 Oct 9. Immunity. 2018. PMID: 30314758 Free PMC article.
Extrafollicular responses in humans and SLE.
Jenks SA, Cashman KS, Woodruff MC, Lee FE, Sanz I. Jenks SA, et al. Among authors: woodruff mc. Immunol Rev. 2019 Mar;288(1):136-148. doi: 10.1111/imr.12741. Immunol Rev. 2019. PMID: 30874345 Free PMC article. Review.
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.
Jenks SA, Cashman KS, Zumaquero E, Marigorta UM, Patel AV, Wang X, Tomar D, Woodruff MC, Simon Z, Bugrovsky R, Blalock EL, Scharer CD, Tipton CM, Wei C, Lim SS, Petri M, Niewold TB, Anolik JH, Gibson G, Eun-Hyung Lee F, Boss JM, Lund FE, Sanz I. Jenks SA, et al. Among authors: woodruff mc. Immunity. 2020 Jan 14;52(1):203. doi: 10.1016/j.immuni.2019.12.005. Immunity. 2020. PMID: 31940271 Free PMC article. No abstract available.
Dominant extrafollicular B cell responses in severe COVID-19 disease correlate with robust viral-specific antibody production but poor clinical outcomes.
Woodruff M, Ramonell R, Cashman K, Nguyen D, Saini A, Haddad N, Ley A, Kyu S, Howell JC, Ozturk T, Lee S, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam F, Sharma M, Wu H, Le S, Jenks S, Tipton CM, Hu W, Lee FE, Sanz I. Woodruff M, et al. medRxiv [Preprint]. 2020 Jun 22:2020.04.29.20083717. doi: 10.1101/2020.04.29.20083717. medRxiv. 2020. PMID: 32511635 Free PMC article. Updated. Preprint.
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.
Woodruff MC, Ramonell RP, Nguyen DC, Cashman KS, Saini AS, Haddad NS, Ley AM, Kyu S, Howell JC, Ozturk T, Lee S, Suryadevara N, Case JB, Bugrovsky R, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam FA, Sharma M, Wu HM, Le SN, Jenks SA, Tipton CM, Staitieh B, Daiss JL, Ghosn E, Diamond MS, Carnahan RH, Crowe JE Jr, Hu WT, Lee FE, Sanz I. Woodruff MC, et al. Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z. Epub 2020 Oct 7. Nat Immunol. 2020. PMID: 33028979 Free PMC article.
Relaxed peripheral tolerance drives broad de novo autoreactivity in severe COVID-19.
Woodruff MC, Ramonell RP, Saini AS, Haddad NS, Anam FA, Rudolph ME, Bugrovsky R, Hom J, Cashman KS, Nguyen DC, Kyu S, Piazza M, Tipton CM, Jenks SA, Lee FE, Sanz I. Woodruff MC, et al. medRxiv [Preprint]. 2021 Jul 27:2020.10.21.20216192. doi: 10.1101/2020.10.21.20216192. medRxiv. 2021. PMID: 33106819 Free PMC article. Updated. Preprint.
43 results