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Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Butler CC, Hobbs FDR, Gbinigie OA, Rahman NM, Hayward G, Richards DB, Dorward J, Lowe DM, Standing JF, Breuer J, Khoo S, Petrou S, Hood K, Nguyen-Van-Tam JS, Patel MG, Saville BR, Marion J, Ogburn E, Allen J, Rutter H, Francis N, Thomas NPB, Evans P, Dobson M, Madden TA, Holmes J, Harris V, Png ME, Lown M, van Hecke O, Detry MA, Saunders CT, Fitzgerald M, Berry NS, Mwandigha L, Galal U, Mort S, Jani BD, Hart ND, Ahmed H, Butler D, McKenna M, Chalk J, Lavallee L, Hadley E, Cureton L, Benysek M, Andersson M, Coates M, Barrett S, Bateman C, Davies JC, Raymundo-Wood I, Ustianowski A, Carson-Stevens A, Yu LM, Little P; PANORAMIC Trial Collaborative Group. Butler CC, et al. Lancet. 2023 Jan 28;401(10373):281-293. doi: 10.1016/S0140-6736(22)02597-1. Epub 2022 Dec 22. Lancet. 2023. PMID: 36566761 Free PMC article. Clinical Trial.
Human models for COVID-19 research.
Woodall MNJ, Masonou T, Case KM, Smith CM. Woodall MNJ, et al. J Physiol. 2021 Sep;599(18):4255-4267. doi: 10.1113/JP281499. Epub 2021 Aug 17. J Physiol. 2021. PMID: 34287894 Free PMC article.
Lung viral infection modelling in a bioengineered whole-organ.
Tommasini F, Benoist T, Shibuya S, Woodall MNJ, Naldi E, Palor M, Orr JC, Giobbe GG, Maughan EF, Saleh T, Gjinovci A, Hutchinson JC, Arthurs OJ, Janes SM, Elvassore N, Hynds RE, Smith CM, Michielin F, Pellegata AF, De Coppi P. Tommasini F, et al. Among authors: woodall mnj. Biomaterials. 2023 Oct;301:122203. doi: 10.1016/j.biomaterials.2023.122203. Epub 2023 Jun 21. Biomaterials. 2023. PMID: 37515903 Free PMC article.
Age-specific nasal epithelial responses to SARS-CoV-2 infection.
Woodall MNJ, Cujba AM, Worlock KB, Case KM, Masonou T, Yoshida M, Polanski K, Huang N, Lindeboom RGH, Mamanova L, Bolt L, Richardson L, Cakir B, Ellis S, Palor M, Burgoyne T, Pinto A, Moulding D, McHugh TD, Saleh A, Kilich E, Mehta P, O'Callaghan C, Zhou J, Barclay W, DeCoppi P, Butler CR, Cortina-Borja M, Vinette H, Roy S, Breuer J, Chambers RC, Heywood WE, Mills K, Hynds RE, Teichmann SA, Meyer KB, Nikolić MZ, Smith CM. Woodall MNJ, et al. Nat Microbiol. 2024 May;9(5):1293-1311. doi: 10.1038/s41564-024-01658-1. Epub 2024 Apr 15. Nat Microbiol. 2024. PMID: 38622380 Free PMC article.
Cell-intrinsic differences between human airway epithelial cells from children and adults.
Maughan EF, Hynds RE, Pennycuick A, Nigro E, Gowers KHC, Denais C, Gómez-López S, Lazarus KA, Orr JC, Pearce DR, Clarke SE, Lee DDH, Woodall MNJ, Masonou T, Case KM, Teixeira VH, Hartley BE, Hewitt RJ, Al Yaghchi C, Sandhu GS, Birchall MA, O'Callaghan C, Smith CM, De Coppi P, Butler CR, Janes SM. Maughan EF, et al. Among authors: woodall mnj. iScience. 2022 Oct 20;25(11):105409. doi: 10.1016/j.isci.2022.105409. eCollection 2022 Nov 18. iScience. 2022. PMID: 36388965 Free PMC article.