Wong NS - Search Results

1

Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations.

Khor CC, Winter S, Sutiman N, Mürdter TE, Chen S, Lim JSL, Li Z, Li J, Sim KS, Ganchev B, Eccles D, Eccles B, Tapper W, Zgheib NK, Tfayli A, Ng RCH, Yap YS, Lim E, Wong M, Wong NS, Ang PCS, Dent R, Tremmel R, Klein K, Schaeffeler E, Zhou Y, Lauschke VM, Eichelbaum M, Schwab M, Brauch HB, Chowbay B, Schroth W. Khor CC, et al. Among authors: wong ns, wong m. Clin Pharmacol Ther. 2023 Mar;113(3):712-723. doi: 10.1002/cpt.2846. Epub 2023 Jan 31. Clin Pharmacol Ther. 2023. PMID: 36629403

2

Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen-treated Asian breast cancer patients.

Lim JS, Sutiman N, Muerdter TE, Singh O, Cheung YB, Ng RC, Yap YS, Wong NS, Ang PC, Dent R, Schroth W, Schwab M, Chowbay B. Lim JS, et al. Among authors: wong ns. Br J Clin Pharmacol. 2016 Jun;81(6):1142-52. doi: 10.1111/bcp.12886. Epub 2016 Mar 8. Br J Clin Pharmacol. 2016. PMID: 26799162 Free PMC article.

3

Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients.

Lim JS, Chen XA, Singh O, Yap YS, Ng RC, Wong NS, Wong M, Lee EJ, Chowbay B. Lim JS, et al. Among authors: wong ns, wong m. Br J Clin Pharmacol. 2011 May;71(5):737-50. doi: 10.1111/j.1365-2125.2011.03905.x. Br J Clin Pharmacol. 2011. PMID: 21480951 Free PMC article.

4

Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer.

Saladores P, Mürdter T, Eccles D, Chowbay B, Zgheib NK, Winter S, Ganchev B, Eccles B, Gerty S, Tfayli A, Lim JS, Yap YS, Ng RC, Wong NS, Dent R, Habbal MZ, Schaeffeler E, Eichelbaum M, Schroth W, Schwab M, Brauch H. Saladores P, et al. Among authors: wong ns. Pharmacogenomics J. 2015 Feb;15(1):84-94. doi: 10.1038/tpj.2014.34. Epub 2014 Aug 5. Pharmacogenomics J. 2015. PMID: 25091503 Free PMC article.

5

Pharmacogenetics of UGT1A4, UGT2B7 and UGT2B15 and Their Influence on Tamoxifen Disposition in Asian Breast Cancer Patients.

Sutiman N, Lim JSL, Muerdter TE, Singh O, Cheung YB, Ng RCH, Yap YS, Wong NS, Ang PCS, Dent R, Schroth W, Schwab M, Khor CC, Chowbay B. Sutiman N, et al. Among authors: wong ns. Clin Pharmacokinet. 2016 Oct;55(10):1239-1250. doi: 10.1007/s40262-016-0402-7. Clin Pharmacokinet. 2016. PMID: 27098059

6

Phase I/II study of gemcitabine with pegylated liposomal doxorubicin as first-line therapy in Asian women with metastatic breast cancer.

Wong ZW, Ang PC, Chowbay B, Wong NS, See HT, Khoo KS. Wong ZW, et al. Among authors: wong ns. Breast. 2008 Oct;17(5):517-22. doi: 10.1016/j.breast.2008.03.009. Epub 2008 May 23. Breast. 2008. PMID: 18502128 Free article. Clinical Trial.

7

PXR pharmacogenetics: association of haplotypes with hepatic CYP3A4 and ABCB1 messenger RNA expression and doxorubicin clearance in Asian breast cancer patients.

Sandanaraj E, Lal S, Selvarajan V, Ooi LL, Wong ZW, Wong NS, Ang PC, Lee EJ, Chowbay B. Sandanaraj E, et al. Among authors: wong zw, wong ns. Clin Cancer Res. 2008 Nov 1;14(21):7116-26. doi: 10.1158/1078-0432.CCR-08-0411. Clin Cancer Res. 2008. PMID: 18981011 Free article.

8

Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population.

Chan M, Ji SM, Liaw CS, Yap YS, Law HY, Yoon CS, Wong CY, Yong WS, Wong NS, Ng R, Ong KW, Madhukumar P, Oey CL, Tan PH, Li HH, Ang P, Ho GH, Lee AS. Chan M, et al. Among authors: wong ns, wong cy. Breast Cancer Res Treat. 2012 Nov;136(1):209-20. doi: 10.1007/s10549-012-2234-y. Epub 2012 Sep 11. Breast Cancer Res Treat. 2012. PMID: 22965832

9

Measurement properties of the English and Chinese versions of the Functional Assessment of Cancer Therapy-Breast (FACT-B) in Asian breast cancer patients.

Ng R, Lee CF, Wong NS, Luo N, Yap YS, Lo SK, Chia WK, Yee A, Krishna L, Goh C, Cheung YB. Ng R, et al. Among authors: wong ns. Breast Cancer Res Treat. 2012 Jan;131(2):619-25. doi: 10.1007/s10549-011-1764-z. Epub 2011 Sep 16. Breast Cancer Res Treat. 2012. PMID: 21922244

10

Pharmacogenetics of ABCB5, ABCC5 and RLIP76 and doxorubicin pharmacokinetics in Asian breast cancer patients.

Lal S, Sutiman N, Ooi LL, Wong ZW, Wong NS, Ang PCS, Chowbay B. Lal S, et al. Among authors: wong zw, wong ns. Pharmacogenomics J. 2017 Jul;17(4):337-343. doi: 10.1038/tpj.2016.17. Epub 2016 Mar 15. Pharmacogenomics J. 2017. PMID: 26975227

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