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Histotype-specific copy-number alterations in ovarian cancer.
Huang RY, Chen GB, Matsumura N, Lai HC, Mori S, Li J, Wong MK, Konishi I, Thiery JP, Goh L. Huang RY, et al. Among authors: wong mk. BMC Med Genomics. 2012 Oct 18;5:47. doi: 10.1186/1755-8794-5-47. BMC Med Genomics. 2012. PMID: 23078675 Free PMC article.
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer.
Tan TZ, Miow QH, Huang RY, Wong MK, Ye J, Lau JA, Wu MC, Bin Abdul Hadi LH, Soong R, Choolani M, Davidson B, Nesland JM, Wang LZ, Matsumura N, Mandai M, Konishi I, Goh BC, Chang JT, Thiery JP, Mori S. Tan TZ, et al. Among authors: wong mk. EMBO Mol Med. 2013 Jul;5(7):1051-66. doi: 10.1002/emmm.201201823. Epub 2013 May 13. EMBO Mol Med. 2013. PMID: 23666744 Free PMC article.
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530).
Huang RY, Wong MK, Tan TZ, Kuay KT, Ng AH, Chung VY, Chu YS, Matsumura N, Lai HC, Lee YF, Sim WJ, Chai C, Pietschmann E, Mori S, Low JJ, Choolani M, Thiery JP. Huang RY, et al. Among authors: wong mk. Cell Death Dis. 2013 Nov 7;4(11):e915. doi: 10.1038/cddis.2013.442. Cell Death Dis. 2013. PMID: 24201814 Free PMC article.
Neuroblastoma patient-derived cultures are enriched for a mesenchymal gene signature and reflect individual drug response.
Hee E, Wong MK, Tan SH, Choo Z, Kuick CH, Ling S, Yong MH, Jain S, Lian DWQ, Ng EHQ, Yong YFL, Ren MH, Syed Sulaiman N, Low SYY, Chua YW, Syed MF, Lim TKH, Soh SY, Iyer P, Seng MSF, Lam JCM, Tan EEK, Chan MY, Tan AM, Chen Y, Chen Z, Chang KTE, Loh AHP. Hee E, et al. Among authors: wong mk. Cancer Sci. 2020 Oct;111(10):3780-3792. doi: 10.1111/cas.14610. Epub 2020 Aug 28. Cancer Sci. 2020. PMID: 32777141 Free PMC article.
Pro-metastatic and mesenchymal gene expression signatures characterize circulating tumor cells of neuroblastoma patients with bone marrow metastases and relapse.
Loh AHP, Angelina C, Wong MK, Tan SH, Sukhatme SA, Yeo T, Lim SB, Lee YT, Soh SY, Leung W, Chang KTE, Chua YW, Alkaff SMF, Lim TKH, Lim CT, Chen ZX. Loh AHP, et al. Among authors: wong mk. Front Oncol. 2022 Sep 13;12:939460. doi: 10.3389/fonc.2022.939460. eCollection 2022. Front Oncol. 2022. PMID: 36176417 Free PMC article.
Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma.
Wong RLY, Wong MRE, Kuick CH, Saffari SE, Wong MK, Tan SH, Merchant K, Chang KTE, Thangavelu M, Periyasamy G, Chen ZX, Iyer P, Tan EEK, Soh SY, Iyer NG, Fan Q, Loh AHP. Wong RLY, et al. Among authors: wong mre, wong mk. Front Oncol. 2021 Oct 14;11:709525. doi: 10.3389/fonc.2021.709525. eCollection 2021. Front Oncol. 2021. PMID: 34722256 Free PMC article.
615 results