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Single cell analysis of cribriform prostate cancer reveals cell intrinsic and tumor microenvironmental pathways of aggressive disease.
Wong HY, Sheng Q, Hesterberg AB, Croessmann S, Rios BL, Giri K, Jackson J, Miranda AX, Watkins E, Schaffer KR, Donahue M, Winkler E, Penson DF, Smith JA, Herrell SD, Luckenbaugh AN, Barocas DA, Kim YJ, Graves D, Giannico GA, Rathmell JC, Park BH, Gordetsky JB, Hurley PJ. Wong HY, et al. Nat Commun. 2022 Oct 13;13(1):6036. doi: 10.1038/s41467-022-33780-1. Nat Commun. 2022. PMID: 36229464 Free PMC article.
Hierarchical tumor heterogeneity mediated by cell contact between distinct genetic subclones.
Karthikeyan S, Waters IG, Dennison L, Chu D, Donaldson J, Shin DH, Rosen DM, Gonzalez-Ericsson PI, Sanchez V, Sanders ME, Pantone MV, Bergman RE, Davidson BA, Reed SC, Zabransky DJ, Cravero K, Kyker-Snowman K, Button B, Wong HY, Hurley PJ, Croessmann S, Park BH. Karthikeyan S, et al. Among authors: wong hy. J Clin Invest. 2021 Mar 15;131(6):e143557. doi: 10.1172/JCI143557. J Clin Invest. 2021. PMID: 33529175 Free PMC article.
NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model.
Cravero K, Pantone MV, Shin DH, Bergman R, Cochran R, Chu D, Zabransky DJ, Karthikeyan S, Waters IG, Hunter N, Rosen DM, Kyker-Snowman K, Dalton WB, Button B, Shinn D, Wong HY, Donaldson J, Hurley PJ, Croessmann S, Park BH. Cravero K, et al. Among authors: wong hy. Oncotarget. 2022 Feb 16;13:373-386. doi: 10.18632/oncotarget.28200. eCollection 2022. Oncotarget. 2022. PMID: 35186194 Free PMC article.
Plasma tumor DNA: on your markers, get set, go!
Wong HY, Park BH. Wong HY, et al. Ann Transl Med. 2014 Jan;2(1):2. doi: 10.3978/j.issn.2305-5839.2013.06.07. Ann Transl Med. 2014. PMID: 25332978 Free PMC article.
Comparison of cell stabilizing blood collection tubes for circulating plasma tumor DNA.
Toro PV, Erlanger B, Beaver JA, Cochran RL, VanDenBerg DA, Yakim E, Cravero K, Chu D, Zabransky DJ, Wong HY, Croessmann S, Parsons H, Hurley PJ, Lauring J, Park BH. Toro PV, et al. Among authors: wong hy. Clin Biochem. 2015 Oct;48(15):993-8. doi: 10.1016/j.clinbiochem.2015.07.097. Epub 2015 Jul 31. Clin Biochem. 2015. PMID: 26234639 Free PMC article.
Ki-67 is required for maintenance of cancer stem cells but not cell proliferation.
Cidado J, Wong HY, Rosen DM, Cimino-Mathews A, Garay JP, Fessler AG, Rasheed ZA, Hicks J, Cochran RL, Croessmann S, Zabransky DJ, Mohseni M, Beaver JA, Chu D, Cravero K, Christenson ES, Medford A, Mattox A, De Marzo AM, Argani P, Chawla A, Hurley PJ, Lauring J, Park BH. Cidado J, et al. Among authors: wong hy. Oncotarget. 2016 Feb 2;7(5):6281-93. doi: 10.18632/oncotarget.7057. Oncotarget. 2016. PMID: 26823390 Free PMC article.
ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.
Chu D, Paoletti C, Gersch C, VanDenBerg DA, Zabransky DJ, Cochran RL, Wong HY, Toro PV, Cidado J, Croessmann S, Erlanger B, Cravero K, Kyker-Snowman K, Button B, Parsons HA, Dalton WB, Gillani R, Medford A, Aung K, Tokudome N, Chinnaiyan AM, Schott A, Robinson D, Jacks KS, Lauring J, Hurley PJ, Hayes DF, Rae JM, Park BH. Chu D, et al. Among authors: wong hy. Clin Cancer Res. 2016 Feb 15;22(4):993-9. doi: 10.1158/1078-0432.CCR-15-0943. Epub 2015 Aug 10. Clin Cancer Res. 2016. PMID: 26261103 Free PMC article.
MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.
Mohseni M, Cidado J, Croessmann S, Cravero K, Cimino-Mathews A, Wong HY, Scharpf R, Zabransky DJ, Abukhdeir AM, Garay JP, Wang GM, Beaver JA, Cochran RL, Blair BG, Rosen DM, Erlanger B, Argani P, Hurley PJ, Lauring J, Park BH. Mohseni M, et al. Among authors: wong hy. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17606-11. doi: 10.1073/pnas.1408650111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422431 Free PMC article.
322 results