Wong AL - Search Results

1

Targeting Hypoxia-Inducible Factor-1-Mediated Metastasis for Cancer Therapy.

Ma Z, Wang LZ, Cheng JT, Lam WST, Ma X, Xiang X, Wong AL, Goh BC, Gong Q, Sethi G, Wang L. Ma Z, et al. Among authors: wong al. Antioxid Redox Signal. 2021 Jun 20;34(18):1484-1497. doi: 10.1089/ars.2019.7935. Epub 2021 Jan 25. Antioxid Redox Signal. 2021. PMID: 33198508 Review.

2

Gemcitabine and platinum pathway pharmacogenetics in Asian breast cancer patients.

Wong AL, Yap HL, Yeo WL, Soong R, Ng SS, Wang LZ, Cordero MT, Yong WP, Goh BC, Lee SC. Wong AL, et al. Cancer Genomics Proteomics. 2011 Sep-Oct;8(5):255-9. Cancer Genomics Proteomics. 2011. PMID: 21980041

3

Glucuronidation by UGT1A1 is the dominant pathway of the metabolic disposition of belinostat in liver cancer patients.

Wang LZ, Ramírez J, Yeo W, Chan MY, Thuya WL, Lau JY, Wan SC, Wong AL, Zee YK, Lim R, Lee SC, Ho PC, Lee HS, Chan A, Ansher S, Ratain MJ, Goh BC. Wang LZ, et al. Among authors: wong al. PLoS One. 2013;8(1):e54522. doi: 10.1371/journal.pone.0054522. Epub 2013 Jan 30. PLoS One. 2013. PMID: 23382909 Free PMC article. Clinical Trial.

4

Validation of a rapid and sensitive LC-MS/MS method for determination of exemestane and its metabolites, 17β-hydroxyexemestane and 17β-hydroxyexemestane-17-O-β-D-glucuronide: application to human pharmacokinetics study.

Wang LZ, Goh SH, Wong AL, Thuya WL, Lau JY, Wan SC, Lee SC, Ho PC, Goh BC. Wang LZ, et al. Among authors: wong al. PLoS One. 2015 Mar 20;10(3):e0118553. doi: 10.1371/journal.pone.0118553. eCollection 2015. PLoS One. 2015. PMID: 25793887 Free PMC article.

5

Dose modifications in Asian cancer patients with hepatic dysfunction receiving weekly docetaxel: A prospective pharmacokinetic and safety study.

Syn NL, Wang L, Wong AL, Soe MY, Chuah B, Chan D, Tan SH, Soo RA, Lee SC, Goh BC, Yong WP. Syn NL, et al. Among authors: wong al. Cancer Sci. 2016 Feb;107(2):173-80. doi: 10.1111/cas.12856. Epub 2016 Feb 8. Cancer Sci. 2016. PMID: 26663719 Free PMC article. Clinical Trial.

6

Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development.

Wang L, Phan DD, Zhang J, Ong PS, Thuya WL, Soo R, Wong AL, Yong WP, Lee SC, Ho PC, Sethi G, Goh BC. Wang L, et al. Among authors: wong al. Oncotarget. 2016 Jul 12;7(28):44790-44802. doi: 10.18632/oncotarget.8316. Oncotarget. 2016. PMID: 27027349 Free PMC article. Review.

7

Pharmacogenetics-Guided Phase I Study of Capecitabine on an Intermittent Schedule in Patients with Advanced or Metastatic Solid Tumours.

Soo RA, Syn N, Lee SC, Wang L, Lim XY, Loh M, Tan SH, Zee YK, Wong AL, Chuah B, Chan D, Lim SE, Goh BC, Soong R, Yong WP. Soo RA, et al. Among authors: wong al. Sci Rep. 2016 Jun 14;6:27826. doi: 10.1038/srep27826. Sci Rep. 2016. PMID: 27296624 Free PMC article. Clinical Trial.

8

A novel combinatorial strategy using Seliciclib(®) and Belinostat(®) for eradication of non-small cell lung cancer via apoptosis induction and BID activation.

Ong PS, Wang L, Chia DM, Seah JY, Kong LR, Thuya WL, Chinnathambi A, Lau JY, Wong AL, Yong WP, Yang D, Ho PC, Sethi G, Goh BC. Ong PS, et al. Among authors: wong al. Cancer Lett. 2016 Oct 10;381(1):49-57. doi: 10.1016/j.canlet.2016.07.023. Epub 2016 Jul 25. Cancer Lett. 2016. PMID: 27461583

9

Combined use of irinotecan with histone deacetylase inhibitor belinostat could cause severe toxicity by inhibiting SN-38 glucuronidation via UGT1A1.

Wang L, Chan CEL, Wong AL, Wong FC, Lim SW, Chinnathambi A, Alharbi SA, Lee LS, Soo R, Yong WP, Lee SC, Ho PC, Sethi G, Goh BC. Wang L, et al. Among authors: wong fc, wong al. Oncotarget. 2017 Jun 20;8(25):41572-41581. doi: 10.18632/oncotarget.15017. Oncotarget. 2017. PMID: 28157715 Free PMC article.

10

Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling.

Wang L, Syn NL, Subhash VV, Any Y, Thuya WL, Cheow ESH, Kong L, Yu F, Peethala PC, Wong AL, Laljibhai HJ, Chinnathambi A, Ong PS, Ho PC, Sethi G, Yong WP, Goh BC. Wang L, et al. Among authors: wong al. Cancer Lett. 2018 Mar 28;417:152-160. doi: 10.1016/j.canlet.2017.12.030. Epub 2018 Jan 4. Cancer Lett. 2018. PMID: 29306016

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