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Loss of maternal Trim28 causes male-predominant early embryonic lethality.
Sampath Kumar A, Seah MK, Ling KY, Wang Y, Tan JH, Nitsch S, Lim SL, Lorthongpanich C, Wollmann H, Low DH, Guccione E, Messerschmidt DM. Sampath Kumar A, et al. Among authors: wollmann h. Genes Dev. 2017 Jan 1;31(1):12-17. doi: 10.1101/gad.291195.116. Epub 2017 Jan 23. Genes Dev. 2017. PMID: 28115466 Free PMC article.
CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I.
Palmer N, Talib SZA, Ratnacaram CK, Low D, Bisteau X, Lee JHS, Pfeiffenberger E, Wollmann H, Tan JHL, Wee S, Sobota R, Gunaratne J, Messerschmidt DM, Guccione E, Kaldis P. Palmer N, et al. Among authors: wollmann h. J Cell Biol. 2019 Sep 2;218(9):2896-2918. doi: 10.1083/jcb.201903125. Epub 2019 Jul 26. J Cell Biol. 2019. PMID: 31350280 Free PMC article.
PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.
Mzoughi S, Zhang J, Hequet D, Teo SX, Fang H, Xing QR, Bezzi M, Seah MKY, Ong SLM, Shin EM, Wollmann H, Wong ESM, Al-Haddawi M, Stewart CL, Tergaonkar V, Loh YH, Dunn NR, Messerschmidt DM, Guccione E. Mzoughi S, et al. Among authors: wollmann h. Nat Genet. 2017 Sep;49(9):1354-1363. doi: 10.1038/ng.3922. Epub 2017 Jul 24. Nat Genet. 2017. PMID: 28740264
Loss of hepatocyte cell division leads to liver inflammation and fibrosis.
Dewhurst MR, Ow JR, Zafer G, van Hul NKM, Wollmann H, Bisteau X, Brough D, Choi H, Kaldis P. Dewhurst MR, et al. Among authors: wollmann h. PLoS Genet. 2020 Nov 4;16(11):e1009084. doi: 10.1371/journal.pgen.1009084. eCollection 2020 Nov. PLoS Genet. 2020. PMID: 33147210 Free PMC article.
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.
Mzoughi S, Fong JY, Papadopoli D, Koh CM, Hulea L, Pigini P, Di Tullio F, Andreacchio G, Hoppe MM, Wollmann H, Low D, Caldez MJ, Peng Y, Torre D, Zhao JN, Uchenunu O, Varano G, Motofeanu CM, Lakshmanan M, Teo SX, Wun CM, Perini G, Tan SY, Ong CB, Al-Haddawi M, Rajarethinam R, Hue SS, Lim ST, Ong CK, Huang D, Ng SB, Bernstein E, Hasson D, Wee KB, Kaldis P, Jeyasekharan A, Dominguez-Sola D, Topisirovic I, Guccione E. Mzoughi S, et al. Among authors: wollmann h. Nat Commun. 2020 Jul 14;11(1):3520. doi: 10.1038/s41467-020-17064-0. Nat Commun. 2020. PMID: 32665551 Free PMC article.
216 results