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Volanesorsen to Prevent Acute Pancreatitis in Hypertriglyceridemia.
Alexander VJ, Karwatowska-Prokopczuk E, Prohaska TA, Li L, Geary RS, Gouni-Berthold I, Oral EA, Hegele RA, Stroes ESG, Witztum JL, Tsimikas S. Alexander VJ, et al. Among authors: witztum jl. N Engl J Med. 2024 Feb 1;390(5):476-477. doi: 10.1056/NEJMc2306575. N Engl J Med. 2024. PMID: 38294982 No abstract available.
Assessment of efficacy and safety of volanesorsen for treatment of metabolic complications in patients with familial partial lipodystrophy: Results of the BROADEN study: Volanesorsen in FPLD; The BROADEN Study.
Oral EA, Garg A, Tami J, Huang EA, O'Dea LSL, Schmidt H, Tiulpakov A, Mertens A, Alexander VJ, Watts L, Hurh E, Witztum JL, Geary RS, Tsimikas S. Oral EA, et al. Among authors: witztum jl. J Clin Lipidol. 2022 Nov-Dec;16(6):833-849. doi: 10.1016/j.jacl.2022.08.008. Epub 2022 Sep 22. J Clin Lipidol. 2022. PMID: 36402670 Clinical Trial.
Corrigendum to "Volanesorsen and triglyceride levels in familial chylomicronemia syndrome: Long-term efficacy and safety data from patients in an open-label extension trial" [Journal of Clinical Lipidology, Volume 17, Issue 3, May-June 2023, Pages 342-355].
Witztum JL, Gaudet D, Arca M, Jones A, Soran H, Gouni-Berthold I, Stroes ESG, Alexander VJ, Jones R, Watts L, Xia S, Tsimikas S. Witztum JL, et al. J Clin Lipidol. 2023 Oct 13:S1933-2874(23)00273-8. doi: 10.1016/j.jacl.2023.09.010. Online ahead of print. J Clin Lipidol. 2023. PMID: 38565460 No abstract available.
Olezarsen, Acute Pancreatitis, and Familial Chylomicronemia Syndrome.
Stroes ESG, Alexander VJ, Karwatowska-Prokopczuk E, Hegele RA, Arca M, Ballantyne CM, Soran H, Prohaska TA, Xia S, Ginsberg HN, Witztum JL, Tsimikas S; Balance Investigators. Stroes ESG, et al. Among authors: witztum jl. N Engl J Med. 2024 Apr 7. doi: 10.1056/NEJMoa2400201. Online ahead of print. N Engl J Med. 2024. PMID: 38587247
Apolipoprotein C3 induces inflammasome activation only in its delipidated form.
Hsu CC, Shao B, Kanter JE, He Y, Vaisar T, Witztum JL, Snell-Bergeon J, McInnes G, Bruse S, Gottesman O, Mullick AE, Bornfeldt KE. Hsu CC, et al. Among authors: witztum jl. Nat Immunol. 2023 Mar;24(3):408-411. doi: 10.1038/s41590-023-01423-2. Epub 2023 Feb 13. Nat Immunol. 2023. PMID: 36781985 Free PMC article.
469 results