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Next Generation Chemiluminescent Probes for Antimalarial Drug Discovery.
Hellingman A, Sifoniou K, Buser T, Thommen BT, Walz A, Passecker A, Collins J, Hupfeld M, Wittlin S, Witmer K, Brancucci NMB. Hellingman A, et al. Among authors: wittlin s. ACS Infect Dis. 2024 Apr 12;10(4):1286-1297. doi: 10.1021/acsinfecdis.3c00707. Epub 2024 Apr 1. ACS Infect Dis. 2024. PMID: 38556981 Free PMC article.
Identification of a new chemical class of antimalarials.
Brunner R, Aissaoui H, Boss C, Bozdech Z, Brun R, Corminboeuf O, Delahaye S, Fischli C, Heidmann B, Kaiser M, Kamber J, Meyer S, Papastogiannidis P, Siegrist R, Voss T, Welford R, Wittlin S, Binkert C. Brunner R, et al. Among authors: wittlin s. J Infect Dis. 2012 Sep 1;206(5):735-43. doi: 10.1093/infdis/jis418. Epub 2012 Jun 25. J Infect Dis. 2012. PMID: 22732921
Multistage Antiplasmodium Activity of Astemizole Analogues and Inhibition of Hemozoin Formation as a Contributor to Their Mode of Action.
Kumar M, Okombo J, Mambwe D, Taylor D, Lawrence N, Reader J, van der Watt M, Fontinha D, Sanches-Vaz M, Bezuidenhout BC, Lauterbach SB, Liebenberg D, Birkholtz LM, Coetzer TL, Prudêncio M, Egan TJ, Wittlin S, Chibale K. Kumar M, et al. Among authors: wittlin s. ACS Infect Dis. 2019 Feb 8;5(2):303-315. doi: 10.1021/acsinfecdis.8b00272. Epub 2019 Jan 7. ACS Infect Dis. 2019. PMID: 30525439
Stochastic Protein Alkylation by Antimalarial Peroxides.
Jourdan J, Walz A, Matile H, Schmidt A, Wu J, Wang X, Dong Y, Vennerstrom JL, Schmidt RS, Wittlin S, Mäser P. Jourdan J, et al. Among authors: wittlin s. ACS Infect Dis. 2019 Dec 13;5(12):2067-2075. doi: 10.1021/acsinfecdis.9b00264. Epub 2019 Dec 2. ACS Infect Dis. 2019. PMID: 31626733
Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors.
Okaniwa M, Shibata A, Ochida A, Akao Y, White KL, Shackleford DM, Duffy S, Lucantoni L, Dey S, Striepen J, Yeo T, Mok S, Aguiar ACC, Sturm A, Crespo B, Sanz LM, Churchyard A, Baum J, Pereira DB, Guido RVC, Dechering KJ, Wittlin S, Uhlemann AC, Fidock DA, Niles JC, Avery VM, Charman SA, Laleu B. Okaniwa M, et al. Among authors: wittlin s. ACS Infect Dis. 2021 Jun 11;7(6):1680-1689. doi: 10.1021/acsinfecdis.1c00020. Epub 2021 Apr 30. ACS Infect Dis. 2021. PMID: 33929818 Free PMC article.
Diaryl Ureas as an Antiprotozoal Chemotype.
Leas DA, Sanford AG, Wu J, Cal M, Kaiser M, Wittlin S, Hemsley RM, Darner EB, Lui LM, Davis PH, Vennerstrom JL. Leas DA, et al. Among authors: wittlin s. ACS Infect Dis. 2021 Jun 11;7(6):1578-1583. doi: 10.1021/acsinfecdis.1c00135. Epub 2021 May 10. ACS Infect Dis. 2021. PMID: 33971090 Free PMC article.
208 results