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Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation.
Chen CC, Tran W, Song K, Sugimoto T, Obusan MB, Wang L, Sheu KM, Cheng D, Ta L, Varuzhanyan G, Huang A, Xu R, Zeng Y, Borujerdpur A, Bayley NA, Noguchi M, Mao Z, Morrissey C, Corey E, Nelson PS, Zhao Y, Huang J, Park JW, Witte ON, Graeber TG. Chen CC, et al. Among authors: witte on. Cancer Cell. 2023 Dec 11;41(12):2066-2082.e9. doi: 10.1016/j.ccell.2023.10.009. Epub 2023 Nov 22. Cancer Cell. 2023. PMID: 37995683 Free article.
Wild-type C-Raf gene dosage and dimerization drive prostate cancer metastasis.
Ta L, Tsai BL, Deng W, Sha J, Varuzhanyan G, Tran W, Wohlschlegel JA, Carr-Ascher JR, Witte ON. Ta L, et al. Among authors: witte on. iScience. 2023 Nov 17;26(12):108480. doi: 10.1016/j.isci.2023.108480. eCollection 2023 Dec 15. iScience. 2023. PMID: 38089570 Free PMC article.
Defining T cell receptor repertoires using nanovial-based binding and functional screening.
Koo D, Mao Z, Dimatteo R, Noguchi M, Tsubamoto N, McLaughlin J, Tran W, Lee S, Cheng D, de Rutte J, Burton Sojo G, Witte ON, Di Carlo D. Koo D, et al. Among authors: witte on. Proc Natl Acad Sci U S A. 2024 Apr 2;121(14):e2320442121. doi: 10.1073/pnas.2320442121. Epub 2024 Mar 27. Proc Natl Acad Sci U S A. 2024. PMID: 38536748 Free PMC article.
Dual-inhibitory domain iCARs improve the efficiency of the AND-NOT gate CAR T strategy.
Bangayan NJ, Wang L, Burton Sojo G, Noguchi M, Cheng D, Ta L, Gunn D, Mao Z, Liu S, Yin Q, Riedinger M, Li K, Wu AM, Stoyanova T, Witte ON. Bangayan NJ, et al. Among authors: witte on. Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2312374120. doi: 10.1073/pnas.2312374120. Epub 2023 Nov 14. Proc Natl Acad Sci U S A. 2023. PMID: 37963244 Free PMC article.
The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer.
Lundberg A, Zhang M, Aggarwal R, Li H, Zhang L, Foye A, Sjöström M, Chou J, Chang K, Moreno-Rodriguez T, Shrestha R, Baskin A, Zhu X, Weinstein AS, Younger N, Alumkal JJ, Beer TM, Chi KN, Evans CP, Gleave M, Lara PN, Reiter RE, Rettig MB, Witte ON, Wyatt AW, Feng FY, Small EJ, Quigley DA. Lundberg A, et al. Among authors: witte on. Cancer Res. 2023 Aug 15;83(16):2763-2774. doi: 10.1158/0008-5472.CAN-23-0593. Cancer Res. 2023. PMID: 37289025 Free PMC article.
IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing.
Pan Y, Phillips JW, Zhang BD, Noguchi M, Kutschera E, McLaughlin J, Nesterenko PA, Mao Z, Bangayan NJ, Wang R, Tran W, Yang HT, Wang Y, Xu Y, Obusan MB, Cheng D, Lee AH, Kadash-Edmondson KE, Champhekar A, Puig-Saus C, Ribas A, Prins RM, Seet CS, Crooks GM, Witte ON, Xing Y. Pan Y, et al. Among authors: witte on. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2221116120. doi: 10.1073/pnas.2221116120. Epub 2023 May 16. Proc Natl Acad Sci U S A. 2023. PMID: 37192158 Free PMC article.
The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.
Sjöström M, Zhao SG, Levy S, Zhang M, Ning Y, Shrestha R, Lundberg A, Herberts C, Foye A, Aggarwal R, Hua JT, Li H, Bergamaschi A, Maurice-Dror C, Maheshwari A, Chen S, Ng SWS, Ye W, Petricca J, Fraser M, Chesner L, Perry MD, Moreno-Rodriguez T, Chen WS, Alumkal JJ, Chou J, Morgans AK, Beer TM, Thomas GV, Gleave M, Lloyd P, Phillips T, McCarthy E, Haffner MC, Zoubeidi A, Annala M, Reiter RE, Rettig MB, Witte ON, Fong L, Bose R, Huang FW, Luo J, Bjartell A, Lang JM, Mahajan NP, Lara PN, Evans CP, Tran PT, Posadas EM, He C, Cui XL, Huang J, Zwart W, Gilbert LA, Maher CA, Boutros PC, Chi KN, Ashworth A, Small EJ, He HH, Wyatt AW, Quigley DA, Feng FY. Sjöström M, et al. Among authors: witte on. Cancer Res. 2022 Nov 2;82(21):3888-3902. doi: 10.1158/0008-5472.CAN-22-1123. Cancer Res. 2022. PMID: 36251389 Free PMC article.
Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis.
Chen BY, Salas JR, Trias AO, Perez Rodriguez A, Tsang JE, Guemes M, Le TM, Galic Z, Shepard HM, Steinman L, Nathanson DA, Czernin J, Witte ON, Radu CG, Schultz KA, Clark PM. Chen BY, et al. Among authors: witte on. Immunology. 2023 Jan;168(1):152-169. doi: 10.1111/imm.13569. Epub 2022 Sep 4. Immunology. 2023. PMID: 35986643 Free PMC article.
381 results