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Modeling Prion-Like Processing of Tau Protein in Alzheimer's Disease for Pharmaceutical Development.
J Alzheimers Dis. 2018;62(3):1287-1303. doi: 10.3233/JAD-170727.
J Alzheimers Dis. 2018.
PMID: 29226873
Free PMC article.
Review.
Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer's disease.
Wischik CM, Staff RT, Wischik DJ, Bentham P, Murray AD, Storey JM, Kook KA, Harrington CR.
Wischik CM, et al. Among authors: wischik dj.
J Alzheimers Dis. 2015;44(2):705-20. doi: 10.3233/JAD-142874.
J Alzheimers Dis. 2015.
PMID: 25550228
Free article.
Clinical Trial.
Item in Clipboard
Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial.
Gauthier S, Feldman HH, Schneider LS, Wilcock GK, Frisoni GB, Hardlund JH, Moebius HJ, Bentham P, Kook KA, Wischik DJ, Schelter BO, Davis CS, Staff RT, Bracoud L, Shamsi K, Storey JM, Harrington CR, Wischik CM.
Gauthier S, et al. Among authors: wischik dj.
Lancet. 2016 Dec 10;388(10062):2873-2884. doi: 10.1016/S0140-6736(16)31275-2. Epub 2016 Nov 16.
Lancet. 2016.
PMID: 27863809
Free PMC article.
Clinical Trial.
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Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.
Wilcock GK, Gauthier S, Frisoni GB, Jia J, Hardlund JH, Moebius HJ, Bentham P, Kook KA, Schelter BO, Wischik DJ, Davis CS, Staff RT, Vuksanovic V, Ahearn T, Bracoud L, Shamsi K, Marek K, Seibyl J, Riedel G, Storey JMD, Harrington CR, Wischik CM.
Wilcock GK, et al. Among authors: wischik dj.
J Alzheimers Dis. 2018;61(1):435-457. doi: 10.3233/JAD-170560.
J Alzheimers Dis. 2018.
PMID: 29154277
Free PMC article.
Clinical Trial.
Item in Clipboard
Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia.
Shiells H, Schelter BO, Bentham P, Baddeley TC, Rubino CM, Ganesan H, Hammel J, Vuksanovic V, Staff RT, Murray AD, Bracoud L, Wischik DJ, Riedel G, Gauthier S, Jia J, Moebius HJ, Hardlund J, Kipps CM, Kook K, Storey JMD, Harrington CR, Wischik CM.
Shiells H, et al. Among authors: wischik dj.
J Alzheimers Dis. 2020;75(2):501-519. doi: 10.3233/JAD-191173.
J Alzheimers Dis. 2020.
PMID: 32280089
Free PMC article.
Clinical Trial.
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Examination of phosphorylated tau protein as a PHF-precursor at early stage Alzheimer's disease.
Lai RY, Gertz HN, Wischik DJ, Xuereb JH, Mukaetova-Ladinska EB, Harrington CR, Edwards PC, Mena R, Paykel ES, Brayne C, et al.
Lai RY, et al. Among authors: wischik dj.
Neurobiol Aging. 1995 May-Jun;16(3):433-45. doi: 10.1016/0197-4580(95)00041-c.
Neurobiol Aging. 1995.
PMID: 7566351
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Short messages.
Wischik DJ.
Wischik DJ.
Philos Trans A Math Phys Eng Sci. 2008 Jun 13;366(1872):1941-53. doi: 10.1098/rsta.2008.0017.
Philos Trans A Math Phys Eng Sci. 2008.
PMID: 18331986
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