Winner LK - Search Results

1

Biomarkers for predicting disease course in Sanfilippo syndrome: An urgent unmet need in childhood-onset dementia.

Winner LK, Rogers ML, Snel MF, Hemsley KM. Winner LK, et al. J Neurochem. 2023 Aug;166(3):481-496. doi: 10.1111/jnc.15891. Epub 2023 Jun 26. J Neurochem. 2023. PMID: 37357981 Review.

2

Intracisternal enzyme replacement therapy in lysosomal storage diseases: dispersal pathways, regional enzyme concentrations and the effect of posttreatment posture.

Jolly RD, Marshall NR, Marshall J, Hartman A, Hemsley KM, Winner LK. Jolly RD, et al. Among authors: winner lk. Neuropathol Appl Neurobiol. 2013 Oct;39(6):681-92. doi: 10.1111/nan.12010. Neuropathol Appl Neurobiol. 2013. PMID: 23252616

3

Neonatal Bone Marrow Transplantation in MPS IIIA Mice.

Lau AA, Shamsani NJ, Winner LK, Hassiotis S, King BM, Hopwood JJ, Hemsley KM. Lau AA, et al. Among authors: winner lk. JIMD Rep. 2013;8:121-32. doi: 10.1007/8904_2012_169. Epub 2012 Aug 10. JIMD Rep. 2013. PMID: 23430528 Free PMC article.

4

Delivery of therapeutic protein for prevention of neurodegenerative changes: comparison of different CSF-delivery methods.

Marshall NR, Hassiotis S, King B, Rozaklis T, Trim PJ, Duplock SK, Winner LK, Beard H, Snel MF, Jolly RD, Hopwood JJ, Hemsley KM. Marshall NR, et al. Among authors: winner lk. Exp Neurol. 2015 Jan;263:79-90. doi: 10.1016/j.expneurol.2014.09.008. Epub 2014 Sep 22. Exp Neurol. 2015. PMID: 25246230

5

A Preclinical Study Evaluating AAVrh10-Based Gene Therapy for Sanfilippo Syndrome.

Winner LK, Beard H, Hassiotis S, Lau AA, Luck AJ, Hopwood JJ, Hemsley KM. Winner LK, et al. Hum Gene Ther. 2016 May;27(5):363-75. doi: 10.1089/hum.2015.170. Hum Gene Ther. 2016. PMID: 26975339

6

Evaluation of Disease Lesions in the Developing Canine MPS IIIA Brain.

Winner LK, Marshall NR, Jolly RD, Trim PJ, Duplock SK, Snel MF, Hemsley KM. Winner LK, et al. JIMD Rep. 2019;43:91-101. doi: 10.1007/8904_2018_110. Epub 2018 Jun 20. JIMD Rep. 2019. PMID: 29923090 Free PMC article.

7

AAVrh10 Vector Corrects Disease Pathology in MPS IIIA Mice and Achieves Widespread Distribution of SGSH in Large Animal Brains.

Hocquemiller M, Hemsley KM, Douglass ML, Tamang SJ, Neumann D, King BM, Beard H, Trim PJ, Winner LK, Lau AA, Snel MF, Gomila C, Ausseil J, Mei X, Giersch L, Plavsic M, Laufer R. Hocquemiller M, et al. Among authors: winner lk. Mol Ther Methods Clin Dev. 2019 Dec 10;17:174-187. doi: 10.1016/j.omtm.2019.12.001. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2019. PMID: 31909089 Free PMC article.

8

The ovine Type II Gaucher disease model recapitulates aspects of human brain disease.

Winner LK, Beard H, Karageorgos L, Smith NJ, Hopwood JJ, Hemsley KM. Winner LK, et al. Biochim Biophys Acta Mol Basis Dis. 2023 Apr;1869(4):166658. doi: 10.1016/j.bbadis.2023.166658. Epub 2023 Jan 29. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 36720445 Free article.

9

Repetitive, non-invasive imaging of neurodegeneration, and prevention of it with gene replacement, in mice with Sanfilippo syndrome.

Hemsley KM, Beard H, Chidlow G, Mammone T, Winner LK, Neumann D, King B, Snel MF, Trim PJ, Casson RJ. Hemsley KM, et al. Among authors: winner lk. Exp Neurol. 2024 Jan;371:114610. doi: 10.1016/j.expneurol.2023.114610. Epub 2023 Nov 8. Exp Neurol. 2024. PMID: 37944880

10

Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs.

Knights KM, Winner LK, Elliot DJ, Bowalgaha K, Miners JO. Knights KM, et al. Among authors: winner lk. Br J Clin Pharmacol. 2009 Sep;68(3):402-12. doi: 10.1111/j.1365-2125.2009.03469.x. Br J Clin Pharmacol. 2009. PMID: 19740398 Free PMC article.

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