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Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis.
Berghoff SA, Spieth L, Sun T, Hosang L, Schlaphoff L, Depp C, Düking T, Winchenbach J, Neuber J, Ewers D, Scholz P, van der Meer F, Cantuti-Castelvetri L, Sasmita AO, Meschkat M, Ruhwedel T, Möbius W, Sankowski R, Prinz M, Huitinga I, Sereda MW, Odoardi F, Ischebeck T, Simons M, Stadelmann-Nessler C, Edgar JM, Nave KA, Saher G. Berghoff SA, et al. Among authors: winchenbach j. Nat Neurosci. 2021 Jan;24(1):47-60. doi: 10.1038/s41593-020-00757-6. Epub 2020 Dec 21. Nat Neurosci. 2021. PMID: 33349711 Free PMC article.
Dietary cholesterol promotes repair of demyelinated lesions in the adult brain.
Berghoff SA, Gerndt N, Winchenbach J, Stumpf SK, Hosang L, Odoardi F, Ruhwedel T, Böhler C, Barrette B, Stassart R, Liebetanz D, Dibaj P, Möbius W, Edgar JM, Saher G. Berghoff SA, et al. Among authors: winchenbach j. Nat Commun. 2017 Jan 24;8:14241. doi: 10.1038/ncomms14241. Nat Commun. 2017. PMID: 28117328 Free PMC article.
Laquinimod enhances central nervous system barrier functions.
Lühder F, Kebir H, Odoardi F, Litke T, Sonneck M, Alvarez JI, Winchenbach J, Eckert N, Hayardeny L, Sorani E, Lodygin D, Flügel A, Prat A. Lühder F, et al. Among authors: winchenbach j. Neurobiol Dis. 2017 Jun;102:60-69. doi: 10.1016/j.nbd.2017.02.002. Epub 2017 Feb 22. Neurobiol Dis. 2017. PMID: 28235673
Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model.
Berghoff SA, Düking T, Spieth L, Winchenbach J, Stumpf SK, Gerndt N, Kusch K, Ruhwedel T, Möbius W, Saher G. Berghoff SA, et al. Among authors: winchenbach j. Acta Neuropathol Commun. 2017 Dec 1;5(1):94. doi: 10.1186/s40478-017-0497-6. Acta Neuropathol Commun. 2017. PMID: 29195512 Free PMC article.
Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport.
Spieth L, Berghoff SA, Stumpf SK, Winchenbach J, Michaelis T, Watanabe T, Gerndt N, Düking T, Hofer S, Ruhwedel T, Shaib AH, Willig K, Kronenberg K, Karst U, Frahm J, Rhee JS, Minguet S, Möbius W, Kruse N, von der Brelie C, Michels P, Stadelmann C, Hülper P, Saher G. Spieth L, et al. Among authors: winchenbach j. Neurooncol Adv. 2021 Sep 20;3(1):vdab140. doi: 10.1093/noajnl/vdab140. eCollection 2021 Jan-Dec. Neurooncol Adv. 2021. PMID: 34647026 Free PMC article.
Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity.
Altas B, Rhee HJ, Ju A, Solís HC, Karaca S, Winchenbach J, Kaplan-Arabaci O, Schwark M, Ambrozkiewicz MC, Lee C, Spieth L, Wieser GL, Chaugule VK, Majoul I, Hassan MA, Goel R, Wojcik SM, Koganezawa N, Hanamura K, Rotin D, Pichler A, Mitkovski M, de Hoz L, Poulopoulos A, Urlaub H, Jahn O, Saher G, Brose N, Rhee J, Kawabe H. Altas B, et al. Among authors: winchenbach j. J Cell Biol. 2024 Jan 1;223(1):e201902050. doi: 10.1083/jcb.201902050. Epub 2023 Nov 30. J Cell Biol. 2024. PMID: 38032389 Free PMC article.