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A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, Hu X, Bernard SM, Georgeson E, Phelps N, Adachi Y, Kubitz M, Landais E, Umotoy J, Robinson A, Briney B, Wilson IA, Burton DR, Ward AB, Crotty S, Batista FD, Schief WR. Steichen JM, et al. Among authors: willis jr. Science. 2019 Dec 6;366(6470):eaax4380. doi: 10.1126/science.aax4380. Epub 2019 Oct 31. Science. 2019. PMID: 31672916 Free PMC article.
Tissue-specific expressed antibody variable gene repertoires.
Briney BS, Willis JR, Finn JA, McKinney BA, Crowe JE Jr. Briney BS, et al. Among authors: willis jr. PLoS One. 2014 Jun 23;9(6):e100839. doi: 10.1371/journal.pone.0100839. eCollection 2014. PLoS One. 2014. PMID: 24956460 Free PMC article.
Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
Willis JR, Sapparapu G, Murrell S, Julien JP, Singh V, King HG, Xia Y, Pickens JA, LaBranche CC, Slaughter JC, Montefiori DC, Wilson IA, Meiler J, Crowe JE Jr. Willis JR, et al. J Clin Invest. 2015 Jun;125(6):2523-31. doi: 10.1172/JCI80693. Epub 2015 May 18. J Clin Invest. 2015. PMID: 25985274 Free PMC article.
172 results