Williams SV - Search Results

1

Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis.

Lombardi B, Ashford P, Moya-Garcia AA, Rust A, Crawford M, Williams SV, Knowles MA, Katan M, Orengo C, Godovac-Zimmermann J. Lombardi B, et al. Among authors: williams sv. Oncotarget. 2017 Oct 25;8(61):102898-102911. doi: 10.18632/oncotarget.22048. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262532 Free PMC article.

2

Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use.

Patani H, Bunney TD, Thiyagarajan N, Norman RA, Ogg D, Breed J, Ashford P, Potterton A, Edwards M, Williams SV, Thomson GS, Pang CS, Knowles MA, Breeze AL, Orengo C, Phillips C, Katan M. Patani H, et al. Among authors: williams sv. Oncotarget. 2016 Apr 26;7(17):24252-68. doi: 10.18632/oncotarget.8132. Oncotarget. 2016. PMID: 26992226 Free PMC article.

3

Oncogenic FGFR3 gene fusions in bladder cancer.

Williams SV, Hurst CD, Knowles MA. Williams SV, et al. Hum Mol Genet. 2013 Feb 15;22(4):795-803. doi: 10.1093/hmg/dds486. Epub 2012 Nov 21. Hum Mol Genet. 2013. PMID: 23175443 Free PMC article.

4

Fibroblast growth factor receptor (FGFR) alterations in squamous differentiated bladder cancer: a putative therapeutic target for a small subgroup.

Baldia PH, Maurer A, Heide T, Rose M, Stoehr R, Hartmann A, Williams SV, Knowles MA, Knuechel R, Gaisa NT. Baldia PH, et al. Among authors: williams sv. Oncotarget. 2016 Nov 1;7(44):71429-71439. doi: 10.18632/oncotarget.12198. Oncotarget. 2016. PMID: 27669755 Free PMC article.

5

The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study.

Bunney TD, Wan S, Thiyagarajan N, Sutto L, Williams SV, Ashford P, Koss H, Knowles MA, Gervasio FL, Coveney PV, Katan M. Bunney TD, et al. Among authors: williams sv. EBioMedicine. 2015 Mar 1;2(3):194-204. doi: 10.1016/j.ebiom.2015.02.009. EBioMedicine. 2015. PMID: 26097890 Free PMC article.

6

A place for precision medicine in bladder cancer: targeting the FGFRs.

di Martino E, Tomlinson DC, Williams SV, Knowles MA. di Martino E, et al. Among authors: williams sv. Future Oncol. 2016 Oct;12(19):2243-63. doi: 10.2217/fon-2016-0042. Epub 2016 Jul 6. Future Oncol. 2016. PMID: 27381494 Free PMC article. Review.

7

Loss of heterozygosity analysis and DNA copy number measurement on 8p in bladder cancer reveals two mechanisms of allelic loss.

Adams J, Williams SV, Aveyard JS, Knowles MA. Adams J, et al. Among authors: williams sv. Cancer Res. 2005 Jan 1;65(1):66-75. Cancer Res. 2005. PMID: 15665280

8

High-resolution analysis of genomic copy number alterations in bladder cancer by microarray-based comparative genomic hybridization.

Hurst CD, Fiegler H, Carr P, Williams S, Carter NP, Knowles MA. Hurst CD, et al. Oncogene. 2004 Mar 18;23(12):2250-63. doi: 10.1038/sj.onc.1207260. Oncogene. 2004. PMID: 14968109

9

Integrated genomic and transcriptional analysis of the in vitro evolution of telomerase-immortalized urothelial cells (TERT-NHUC).

Chapman EJ, Williams SV, Platt FM, Hurst CD, Chambers P, Roberts P, Knowles MA. Chapman EJ, et al. Among authors: williams sv. Genes Chromosomes Cancer. 2009 Aug;48(8):694-710. doi: 10.1002/gcc.20672. Genes Chromosomes Cancer. 2009. PMID: 19405089

10

Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification.

Hurst CD, Tomlinson DC, Williams SV, Platt FM, Knowles MA. Hurst CD, et al. Among authors: williams sv. Oncogene. 2008 Apr 24;27(19):2716-27. doi: 10.1038/sj.onc.1210934. Epub 2007 Nov 26. Oncogene. 2008. PMID: 18037967 Free PMC article.

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