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Recent advances in lipid-based formulation technology.
Porter CJ, Williams HD, Trevaskis NL. Porter CJ, et al. Among authors: williams hd. Pharm Res. 2013 Dec;30(12):2971-5. doi: 10.1007/s11095-013-1229-7. Epub 2013 Oct 26. Pharm Res. 2013. PMID: 24158727 No abstract available.
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a range of representative formulations.
Williams HD, Sassene P, Kleberg K, Bakala-N'Goma JC, Calderone M, Jannin V, Igonin A, Partheil A, Marchaud D, Jule E, Vertommen J, Maio M, Blundell R, Benameur H, Carrière F, Müllertz A, Porter CJ, Pouton CW. Williams HD, et al. J Pharm Sci. 2012 Sep;101(9):3360-80. doi: 10.1002/jps.23205. Epub 2012 May 29. J Pharm Sci. 2012. PMID: 22644939
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations.
Williams HD, Sassene P, Kleberg K, Calderone M, Igonin A, Jule E, Vertommen J, Blundell R, Benameur H, Müllertz A, Pouton CW, Porter CJ; LFCS Consortium. Williams HD, et al. Pharm Res. 2013 Dec;30(12):3059-76. doi: 10.1007/s11095-013-1038-z. Epub 2013 May 10. Pharm Res. 2013. PMID: 23661145
Choice of nonionic surfactant used to formulate type IIIA self-emulsifying drug delivery systems and the physicochemical properties of the drug have a pronounced influence on the degree of drug supersaturation that develops during in vitro digestion.
Devraj R, Williams HD, Warren DB, Porter CJ, Pouton CW. Devraj R, et al. Among authors: williams hd. J Pharm Sci. 2014 Apr;103(4):1050-63. doi: 10.1002/jps.23856. Epub 2014 Jan 27. J Pharm Sci. 2014. PMID: 24470073
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system.
Williams HD, Sassene P, Kleberg K, Calderone M, Igonin A, Jule E, Vertommen J, Blundell R, Benameur H, Müllertz A, Porter CJ, Pouton CW; Communicated on Behalf of the LFCS Consortium. Williams HD, et al. J Pharm Sci. 2014 Aug;103(8):2441-55. doi: 10.1002/jps.24067. Epub 2014 Jul 1. J Pharm Sci. 2014. PMID: 24985238
119 results