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Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.
Holmen SL, Giambernardi TA, Zylstra CR, Buckner-Berghuis BD, Resau JH, Hess JF, Glatt V, Bouxsein ML, Ai M, Warman ML, Williams BO. Holmen SL, et al. Among authors: williams bo. J Bone Miner Res. 2004 Dec;19(12):2033-40. doi: 10.1359/JBMR.040907. Epub 2004 Sep 13. J Bone Miner Res. 2004. PMID: 15537447 Free article.
Lrp5 functions in bone to regulate bone mass.
Cui Y, Niziolek PJ, MacDonald BT, Zylstra CR, Alenina N, Robinson DR, Zhong Z, Matthes S, Jacobsen CM, Conlon RA, Brommage R, Liu Q, Mseeh F, Powell DR, Yang QM, Zambrowicz B, Gerrits H, Gossen JA, He X, Bader M, Williams BO, Warman ML, Robling AG. Cui Y, et al. Among authors: williams bo. Nat Med. 2011 Jun;17(6):684-91. doi: 10.1038/nm.2388. Epub 2011 May 22. Nat Med. 2011. PMID: 21602802 Free PMC article.
203 results