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IKKα-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines.
Song NY, Li X, Ma B, Willette-Brown J, Zhu F, Jiang C, Su L, Shetty J, Zhao Y, Shi G, Banerjee S, Wu X, Tran B, Nussinov R, Karin M, Hu Y. Song NY, et al. Among authors: willette brown j. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2120956119. doi: 10.1073/pnas.2120956119. Proc Natl Acad Sci U S A. 2022. PMID: 35121655 Free PMC article.
IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways.
Song NY, Zhu F, Wang Z, Willette-Brown J, Xi S, Sun Z, Su L, Wu X, Ma B, Nussinov R, Xia X, Schrump DS, Johnson PF, Karin M, Hu Y. Song NY, et al. Among authors: willette brown j. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E812-E821. doi: 10.1073/pnas.1717520115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311298 Free PMC article.
The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.
Xiao Z, Jiang Q, Willette-Brown J, Xi S, Zhu F, Burkett S, Back T, Song NY, Datla M, Sun Z, Goldszmid R, Lin F, Cohoon T, Pike K, Wu X, Schrump DS, Wong KK, Young HA, Trinchieri G, Wiltrout RH, Hu Y. Xiao Z, et al. Cancer Cell. 2013 Apr 15;23(4):527-40. doi: 10.1016/j.ccr.2013.03.009. Cancer Cell. 2013. PMID: 23597566 Free PMC article.
Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.
Zhu F, Willette-Brown J, Song NY, Lomada D, Song Y, Xue L, Gray Z, Zhao Z, Davis SR, Sun Z, Zhang P, Wu X, Zhan Q, Richie ER, Hu Y. Zhu F, et al. Among authors: willette brown j. Cell Host Microbe. 2017 Apr 12;21(4):478-493.e7. doi: 10.1016/j.chom.2017.03.006. Cell Host Microbe. 2017. PMID: 28407484 Free PMC article.
34 results