Wilkes E - Search Results

1

Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile.

Huang KW, Reebye V, Czysz K, Ciriello S, Dorman S, Reccia I, Lai HS, Peng L, Kostomitsopoulos N, Nicholls J, Habib RS, Tomalia DA, Sætrom P, Wilkes E, Cutillas P, Rossi JJ, Habib NA. Huang KW, et al. Among authors: wilkes e. Mol Ther Nucleic Acids. 2020 Mar 6;19:361-370. doi: 10.1016/j.omtn.2019.10.044. Epub 2019 Nov 21. Mol Ther Nucleic Acids. 2020. PMID: 31877412 Free PMC article.

2

Cross-species proteomics reveals specific modulation of signaling in cancer and stromal cells by phosphoinositide 3-kinase (PI3K) inhibitors.

Rajeeve V, Vendrell I, Wilkes E, Torbett N, Cutillas PR. Rajeeve V, et al. Among authors: wilkes e. Mol Cell Proteomics. 2014 Jun;13(6):1457-70. doi: 10.1074/mcp.M113.035204. Epub 2014 Mar 19. Mol Cell Proteomics. 2014. PMID: 24648465 Free PMC article.

3

Approaches for measuring signalling plasticity in the context of resistance to targeted cancer therapies.

Wilkes EH, Casado P, Cutillas PR. Wilkes EH, et al. Biochem Soc Trans. 2014 Aug;42(4):791-7. doi: 10.1042/BST20140029. Biochem Soc Trans. 2014. PMID: 25109959 Review.

4

Empirical inference of circuitry and plasticity in a kinase signaling network.

Wilkes EH, Terfve C, Gribben JG, Saez-Rodriguez J, Cutillas PR. Wilkes EH, et al. Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7719-24. doi: 10.1073/pnas.1423344112. Epub 2015 Jun 9. Proc Natl Acad Sci U S A. 2015. PMID: 26060313 Free PMC article.

5

Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data.

Terfve CD, Wilkes EH, Casado P, Cutillas PR, Saez-Rodriguez J. Terfve CD, et al. Nat Commun. 2015 Sep 10;6:8033. doi: 10.1038/ncomms9033. Nat Commun. 2015. PMID: 26354681 Free PMC article.

6

NCK Associated Protein 1 Modulated by miRNA-214 Determines Vascular Smooth Muscle Cell Migration, Proliferation, and Neointima Hyperplasia.

Afzal TA, Luong LA, Chen D, Zhang C, Yang F, Chen Q, An W, Wilkes E, Yashiro K, Cutillas PR, Zhang L, Xiao Q. Afzal TA, et al. Among authors: wilkes e. J Am Heart Assoc. 2016 Dec 7;5(12):e004629. doi: 10.1161/JAHA.116.004629. J Am Heart Assoc. 2016. PMID: 27927633 Free PMC article.

7

Oxidative stress downstream of mTORC1 but not AKT causes a proliferative defect in cancer cells resistant to PI3K inhibition.

Dermit M, Casado P, Rajeeve V, Wilkes EH, Foxler DE, Campbell H, Critchlow S, Sharp TV, Gribben JG, Unwin R, Cutillas PR. Dermit M, et al. Among authors: wilkes eh. Oncogene. 2017 May 11;36(19):2762-2774. doi: 10.1038/onc.2016.435. Epub 2016 Dec 19. Oncogene. 2017. PMID: 27991931 Free PMC article.

8

Kinase activity ranking using phosphoproteomics data (KARP) quantifies the contribution of protein kinases to the regulation of cell viability.

Wilkes EH, Casado P, Rajeeve V, Cutillas PR. Wilkes EH, et al. Mol Cell Proteomics. 2017 Sep;16(9):1694-1704. doi: 10.1074/mcp.O116.064360. Epub 2017 Jul 3. Mol Cell Proteomics. 2017. PMID: 28674151 Free PMC article.

9

Label-Free Phosphoproteomic Approach for Kinase Signaling Analysis.

Wilkes E, Cutillas PR. Wilkes E, et al. Methods Mol Biol. 2017;1636:199-217. doi: 10.1007/978-1-4939-7154-1_13. Methods Mol Biol. 2017. PMID: 28730481

10

PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer.

Fearon AE, Carter EP, Clayton NS, Wilkes EH, Baker AM, Kapitonova E, Bakhouche BA, Tanner Y, Wang J, Gadaleta E, Chelala C, Moore KM, Marshall JF, Chupin J, Schmid P, Jones JL, Lockley M, Cutillas PR, Grose RP. Fearon AE, et al. Among authors: wilkes eh. Cell Rep. 2018 Feb 27;22(9):2469-2481. doi: 10.1016/j.celrep.2018.02.028. Cell Rep. 2018. PMID: 29490281 Free PMC article.

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