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Page 1
Whole-genome characterization of myoepithelial carcinomas of the soft tissue.
Cyrta J, Rosiene J, Bareja R, Kudman S, Al Zoughbi W, Motanagh S, Wilkes DC, Eng K, Zhang T, Sticca E, Mathew S, Rubin MA, Sboner A, Elemento O, Rubin BP, Imielinski M, Mosquera JM. Cyrta J, et al. Among authors: wilkes dc. Cold Spring Harb Mol Case Stud. 2022 Dec 28;8(7):a006227. doi: 10.1101/mcs.a006227. Print 2022 Dec. Cold Spring Harb Mol Case Stud. 2022. PMID: 36577525 Free PMC article.
NIPBL::NACC1 Fusion Hepatic Carcinoma.
Hissong E, Al Assaad M, Bal M, Reed KA, Fornelli A, Levine MF, Gundem G, Semaan A, Orr CE, Sakhadeo U, Manohar J, Sigouros M, Wilkes D, Sboner A, Montgomery EA, Graham RP, Medina-Martínez JS, Robine N, Fang JM, Choi EK, Westerhoff M, Delgado-de la Mora J, Caudell P, Yantiss RK, Papaemmanuil E, Elemento O, Sigel C, Jessurun J, Mosquera JM. Hissong E, et al. Am J Surg Pathol. 2024 Feb 1;48(2):183-193. doi: 10.1097/PAS.0000000000002159. Epub 2023 Dec 4. Am J Surg Pathol. 2024. PMID: 38047392
Deciphering the origin and therapeutic targets of cancer of unknown primary: a case report that illustrates the power of integrative whole-exome and transcriptome sequencing analysis.
Al Assaad M, Shin N, Sigouros M, Manohar J, Antysheva Z, Kotlov N, Kiriy D, Nikitina A, Kleimenov M, Tsareva A, Makarova A, Fomchenkova V, Dubinina J, Boyko A, Almog N, Wilkes D, Escalon JG, Saxena A, Elemento O, Sternberg CN, Nanus DM, Mosquera JM. Al Assaad M, et al. Front Oncol. 2024 Jan 22;13:1274163. doi: 10.3389/fonc.2023.1274163. eCollection 2023. Front Oncol. 2024. PMID: 38318324 Free PMC article.
Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer.
Raman R, Villefranc JA, Ullmann TM, Thiesmeyer J, Anelli V, Yao J, Hurley JR, Pauli C, Bareja R, Wha Eng K, Dorsaint P, Wilkes DC, Beg S, Kudman S, Shaw R, Churchill M, Ahmed A, Keefer L, Misner I, Nichol D, Gumpeni N, Scognamiglio T, Rubin MA, Grandori C, Solomon JP, Song W, Mosquera JM, Dephoure N, Sboner A, Elemento O, Houvras Y. Raman R, et al. Among authors: wilkes dc. J Exp Med. 2022 Jun 6;219(6):e20210390. doi: 10.1084/jem.20210390. Epub 2022 May 5. J Exp Med. 2022. PMID: 35510953 Free PMC article.
Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors.
Shohdy KS, Bareja R, Sigouros M, Wilkes DC, Dorsaint P, Manohar J, Bockelman D, Xiang JZ, Kim R, Ohara K, Eng K, Mosquera JM, Elemento O, Sboner A, Alonso A, Faltas BM. Shohdy KS, et al. Among authors: wilkes dc. NPJ Genom Med. 2021 Aug 12;6(1):66. doi: 10.1038/s41525-021-00231-7. NPJ Genom Med. 2021. PMID: 34385467 Free PMC article.
Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.
Sugita M, Wilkes DC, Bareja R, Eng KW, Nataraj S, Jimenez-Flores RA, Yan L, De Leon JP, Croyle JA, Kaner J, Merugu S, Sharma S, MacDonald TY, Noorzad Z, Panchal P, Pancirer D, Cheng S, Xiang JZ, Olson L, Van Besien K, Rickman DS, Mathew S, Tam W, Rubin MA, Beltran H, Sboner A, Hassane DC, Chiosis G, Elemento O, Roboz GJ, Mosquera JM, Guzman ML. Sugita M, et al. Among authors: wilkes dc. NPJ Precis Oncol. 2021 May 26;5(1):44. doi: 10.1038/s41698-021-00183-2. NPJ Precis Oncol. 2021. PMID: 34040147 Free PMC article.
Common germline-somatic variant interactions in advanced urothelial cancer.
Vosoughi A, Zhang T, Shohdy KS, Vlachostergios PJ, Wilkes DC, Bhinder B, Tagawa ST, Nanus DM, Molina AM, Beltran H, Sternberg CN, Motanagh S, Robinson BD, Xiang J, Fan X, Chung WK, Rubin MA, Elemento O, Sboner A, Mosquera JM, Faltas BM. Vosoughi A, et al. Among authors: wilkes dc. Nat Commun. 2020 Dec 3;11(1):6195. doi: 10.1038/s41467-020-19971-8. Nat Commun. 2020. PMID: 33273457 Free PMC article.
Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.
Beg S, Bareja R, Ohara K, Eng KW, Wilkes DC, Pisapia DJ, Zoughbi WA, Kudman S, Zhang W, Rao R, Manohar J, Kane T, Sigouros M, Xiang JZ, Khani F, Robinson BD, Faltas BM, Sternberg CN, Sboner A, Beltran H, Elemento O, Mosquera JM. Beg S, et al. Among authors: wilkes dc. Transl Oncol. 2021 Jan;14(1):100944. doi: 10.1016/j.tranon.2020.100944. Epub 2020 Nov 12. Transl Oncol. 2021. PMID: 33190043 Free PMC article.
Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond SMARCA4 Mutations: A Comprehensive Genomic Analysis.
Auguste A, Blanc-Durand F, Deloger M, Le Formal A, Bareja R, Wilkes DC, Richon C, Brunn B, Caron O, Devouassoux-Shisheboran M, Gouy S, Morice P, Bentivegna E, Sboner A, Elemento O, Rubin MA, Pautier P, Genestie C, Cyrta J, Leary A. Auguste A, et al. Among authors: wilkes dc. Cells. 2020 Jun 19;9(6):1496. doi: 10.3390/cells9061496. Cells. 2020. PMID: 32575483 Free PMC article.
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