Wilczynska A - Search Results

1

Systems analysis of miRNA biomarkers to inform drug safety.

Schofield AL, Brown JP, Brown J, Wilczynska A, Bell C, Glaab WE, Hackl M, Howell L, Lee S, Dear JW, Remes M, Reeves P, Zhang E, Allmer J, Norris A, Falciani F, Takeshita LY, Seyed Forootan S, Sutton R, Park BK, Goldring C. Schofield AL, et al. Among authors: wilczynska a. Arch Toxicol. 2021 Nov;95(11):3475-3495. doi: 10.1007/s00204-021-03150-9. Epub 2021 Sep 12. Arch Toxicol. 2021. PMID: 34510227 Free PMC article. Review.

2

The complexity of miRNA-mediated repression.

Wilczynska A, Bushell M. Wilczynska A, et al. Cell Death Differ. 2015 Jan;22(1):22-33. doi: 10.1038/cdd.2014.112. Epub 2014 Sep 5. Cell Death Differ. 2015. PMID: 25190144 Free PMC article. Review.

3

The emerging role of RNAs in DNA damage repair.

Hawley BR, Lu WT, Wilczynska A, Bushell M. Hawley BR, et al. Among authors: wilczynska a. Cell Death Differ. 2017 Apr;24(4):580-587. doi: 10.1038/cdd.2017.16. Epub 2017 Feb 24. Cell Death Differ. 2017. PMID: 28234355 Free PMC article. Review.

4

MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus.

Godfrey JD, Morton JP, Wilczynska A, Sansom OJ, Bushell MD. Godfrey JD, et al. Among authors: wilczynska a. Cell Death Dis. 2018 May 29;9(6):644. doi: 10.1038/s41419-018-0628-4. Cell Death Dis. 2018. PMID: 29844410 Free PMC article.

5

Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation.

Meijer HA, Kong YW, Lu WT, Wilczynska A, Spriggs RV, Robinson SW, Godfrey JD, Willis AE, Bushell M. Meijer HA, et al. Among authors: wilczynska a. Science. 2013 Apr 5;340(6128):82-5. doi: 10.1126/science.1231197. Science. 2013. PMID: 23559250

6

The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration.

Hall AE, Lu WT, Godfrey JD, Antonov AV, Paicu C, Moxon S, Dalmay T, Wilczynska A, Muller PA, Bushell M. Hall AE, et al. Among authors: wilczynska a. Cell Death Dis. 2016 Apr 7;7(4):e2184. doi: 10.1038/cddis.2016.91. Cell Death Dis. 2016. PMID: 27054339 Free PMC article.

7

Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair.

Lu WT, Hawley BR, Skalka GL, Baldock RA, Smith EM, Bader AS, Malewicz M, Watts FZ, Wilczynska A, Bushell M. Lu WT, et al. Among authors: wilczynska a. Nat Commun. 2018 Feb 7;9(1):532. doi: 10.1038/s41467-018-02893-x. Nat Commun. 2018. PMID: 29416038 Free PMC article.

8

Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by coding sequence composition and mRNA localization.

Gillen SL, Giacomelli C, Hodge K, Zanivan S, Bushell M, Wilczynska A. Gillen SL, et al. Among authors: wilczynska a. Genome Biol. 2021 Oct 6;22(1):284. doi: 10.1186/s13059-021-02494-w. Genome Biol. 2021. PMID: 34615539 Free PMC article.

9

DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity.

Meijer HA, Schmidt T, Gillen SL, Langlais C, Jukes-Jones R, de Moor CH, Cain K, Wilczynska A, Bushell M. Meijer HA, et al. Among authors: wilczynska a. Nucleic Acids Res. 2019 Sep 5;47(15):8224-8238. doi: 10.1093/nar/gkz509. Nucleic Acids Res. 2019. PMID: 31180491 Free PMC article.

10

eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5'UTR.

Wilczynska A, Gillen SL, Schmidt T, Meijer HA, Jukes-Jones R, Langlais C, Kopra K, Lu WT, Godfrey JD, Hawley BR, Hodge K, Zanivan S, Cain K, Le Quesne J, Bushell M. Wilczynska A, et al. Genome Biol. 2019 Dec 2;20(1):262. doi: 10.1186/s13059-019-1857-2. Genome Biol. 2019. PMID: 31791371 Free PMC article.

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